The Synchrony^® Respiratory Tracking System is the first and only commercially available technology that continuously synchronizes beam delivery to the motion of the tumor, allowing clinicians to significantly reduce margins while eliminating the need for gating or breath-holding techniques. With the Synchrony System, physicians no longer have to add significant margins to compensate for a moving target, thus sparing more healthy tissue. It enables the CyberKnife^® Robotic Radiosurgery System to track, detect and correct for tumor and patient movement and synchronizes treatment delivery to the motion of the tumor throughout the respiratory cycle.

Clinical benefits
The Synchrony System allows clinicians, for the first time, to treat complex moving targets with much tighter margins. Clinical benefits include:

• Dynamic tracking of all targets that move with respiration
• Tracking of tumors that move non-linearly
• Improved accuracy of radiation delivery
• Minimized irradiation of healthy tissue or critical structures
• Elimination of complex gating techniques and painful breath-holding techniques (especially for lung patients)
• Easy to learn, easy to use

How the Synchrony System works
Using fiber optic sensing technology, the Synchrony System monitors and tracks the patients’ respiratory motions in real time. By taking advantage of the CyberKnife's high-precision image guidance to locate tumors, the Synchrony System correlates the tumor motion with respiratory motion, dynamically directing the linear accelerator to deliver highly accurate radiation beams to moving tumors. The Synchrony System constantly updates its correlation model with each new X-ray image, automatically correcting for any changes in the patient’s breathing patterns.

The custom-designed Synchrony Vest and Tracking Markers allows for simplified patient setup and marker placement, especially for multi-fraction treatments where the Vest and Markers rarely need to be adjusted on subsequent treatments. Patients breathe normally in complete comfort throughout treatment delivery.

Expanding accurate radiosurgery treatment to all tumors that move with respiration:

• Lung
  
• Pancreas
  
• Liver
  
• Kidney
  
• Other abdominal/thoracic

A multi-center study reported targeting centroid accuracy better than 1.5mm. (Data on file)

In summary, the Synchrony Respiratory Tracking System is revolutionary in that it enables, for the first time, real-time tracking, detecting and correcting for tumors that move with respiration, automatically accounting for any patient movements or changes in respiration.

The Synchrony^® System tracks, detects and corrects
for tumor and patient movement throughout the treatment.