20+ Years of Evidence

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This page presents publications and webinars from around the globe. It includes evidence for a wide range of treatment sites including malignant and benign disease, different fractionation schedules and motion synchronization techniques for both the CyberKnife® and TomoTherapy® platforms. We update new papers on a regular basis. Please take a moment to explore the page and see the evidence we have collected to truly demonstrate how we are making a change to peoples’ lives.

194: Penile Bulb Dose Predicts Sexual Quality of Life after Prostate SBRT: Secondary Analysis of a Multi-Institutional Trial

K. P. Lui, K. Wang, R. C. Chen, B. L. Kane, C. A. Medbery III, K. Underhill Jr, J. R. Gray, A. V. Peddada, and D. B. Fuller | ASTRO | 2022

2026: Efficacy of SBRT in High Volume Metastatic Carcinoma Breast – A Berry Picking Approach in the Era of High Precision Radiotherapy

P.S. Sridhar, P. Anuradha, C. Fareena Taj, S. Suresh, K. Roopesh, R. Ghosh, S. Bj, | ASTRO | 2022

2031: Evaluation of Early Cosmetic Outcome and Toxicity after 5-Fraction Stereotactic Partial Breast Irradiation in Early-Stage Breast Cancer: A Prospective Cohort Study

H.K. Byun, J.S. Chang, H.J. Kim, J. Kim, M.C. Han, S.Y. KIM, R.H. PARK, C.J. Kim, and Y.B. Kim | ASTRO | 2022

3195: Real-World Dose Delivery Accuracy of Prostate SBRT with Tomotherapy Based Target Tracking

L. Goddard, J. Tang, M. K. Garg, W. R. Bodner III, P. Brodin, K. Jeong, and W. A. Tome | ASTRO | 2022

3346: Considerations for CT Number Calibration and Imaging Parameter Selection for Adaptive Planning on a Novel On-Board Helical kVCT System

R. C. Tegtmeier, W. Ferris, R. Chen, J. Miller, J. Bayouth, and W. S. Culberson; WI, | ASTRO | 2022

Hypofractionated Stereotactic Radiotherapy with or without Whole Brain Radiotherapy with Helical Tomotherapy for Multiple Brain Metastases – Long-Term Follow-Up Results of a Phase II Trial

Yuchao Ma | ASTRO | 2022

Potential Clinical Significance of Overall Targeting Accuracy and Motion Management in the Treatment of Tumors That Move With Respiration: Lessons Learnt From a Quarter Century of Stereotactic Body Radiotherapy From Dose Response Models – PubMed (nih.gov)

Mahadevan A, Emami B, Grimm J, Kleinberg LR, Redmond KJ, Welsh JS, Rostock R, Kemmerer E, Forster KM, Stanford J, Shah S, Asbell SO, LaCouture TA, Scofield C, Butterwick I, Xue J, Muacevic A, Adler JR | Front Oncol | 2021

Intensity-modulated radiotherapy versus stereotactic body radiotherapy for prostate cancer (PACE-B): 2-year toxicity results from an open-label, randomised, phase 3, non-inferiority trial

Tree AC, Ostler P, van der Voet H, Chu W, Loblaw A, Ford D, Tolan S, Jain S, Martin A, Staffurth J, Armstrong J, Camilleri P, Kancherla K, Frew J, Chan A, Dayes IS, Duffton A, Brand DH, Henderson D, Morrison K, Brown S, Pugh J, Burnett S, Mahmud M, Hinder V, Naismith O, Hall E, van As N | Lancet Oncol | 2022

Estimation of Annual Secondary Lung Cancer Deaths Using Various Adjuvant Breast Radiotherapy Techniques for Early-Stage Cancers

Jean-Philippe Pignol, Nienke Hoekstra, Derek Wilke, Hannah Dahn, Maureen Nolan, Frank Vicini | Front Oncol | 2021

Skin Toxicity in Early Breast Cancer Patients Treated with Field-In-Field Breast Intensity-Modulated Radiotherapy versus Helical Inverse Breast Intensity-Modulated Radiotherapy: Results of a Phase III Randomised Controlled Trial

K Joseph, L J Vos, Z Gabos, N Pervez, S Chafe, K Tankel, H Warkentin, S Ghosh, J Amanie, K Powell, L-A Polkosnik, S Horsman, M MacKenzie, S Sabri, M B Parliament, J Mackey, B Abdulkarim | Clin Oncol (R Coll Radiol) | 2021

Multi-institutional feasibility study of a fast patient localization method in total marrow irradiation with helical tomotherapy: a global health initiative by the international consortium of total marrow irradiation

Takahashi Y, Vagge S, Agostinelli S, Han E, Matulewicz L, Schubert K, Chityala R, Ratanatharathorn V, Tournel K, Penagaricano JA, Florian S, Mahe MA, Verneris MR, Weisdorf DJ, Corvo R, Dusenbery KE, Storme G, Hui SK | Int J Radiat Oncol Biol Phys | 2015

Fast, simple, and informative patient-specific dose verification method for intensity modulated total marrow irradiation with helical tomotherapy

Takahashi Y, Hui SK | Radiat Oncol | 2014

Extramedullary relapse following total marrow and lymphoid irradiation in patients undergoing allogeneic hematopoietic cell transplantation

Kim JH, Stein A, Tsai N, Schultheiss TE, Palmer J, Liu A, Rosenthal J, Forman SJ, Wong JY | Int J Radiat Oncol Biol Phys | 2014

Total body irradiation in allogeneic bone marrow transplantation conditioning regimens: A review

Paix A, Antoni D, Waissi W, Ledoux MP, Bilger K, Fornecker L, Noel G | Crit Rev Oncol Hematol | 2018

Implementing safe and robust Total Marrow Irradiation using Helical Tomotherapy – A practical guide

Haraldsson A, Engellau J, Lenhoff S, Engelholm S, Bäck S, Engström PE | Phys Med | 2019

Survival and Prognostic Factors of Ultra-Central Tumors Treated with Stereotactic Body Radiotherapy

Salvestrini V, Duijm M, Loi M, Nuyttens JJ | Cancers (Basel) | 2022

Robotic CyberKnife Radiosurgery for the Treatment of Choroidal and Ciliary Body Melanoma

Liegl R, Schmelter V, Fuerweger C, Ehret F, Priglinger S, Muacevic A, Foerster P | Am J Ophthalmol | 2023

Lung Sparing and Ribcage Coverage in Total Body Irradiation Delivered by Helical TomoTherapy

Köksal M, Baumert J, Schoroth F, Scafa D, Koch D, Leitzen C, Sarria GR, Giordano FA, Chatzikonstantinou G, Schmeel LC | Eur J Med Res | 2022

Clinical study of total bone marrow combined with total lymphatic irradiation pretreatment based on tomotherapy in hematopoietic stem cell transplantation of acute leukemia

Fanyang Kong, Shuaipeng Liu, Lele Liu, Yifei Pi, Yuntong Pei, Dandan Xu, Fei Jia, Bin Han, Yuexin Guo | Front Oncol | 2022

Conventionally fractionated radiotherapy versus CyberKnife hypofractionated radiotherapy for painful vertebral haemangiomas – A randomized clinical trial

Marcin Miszczyk, Aleksandra Napieralska, Grzegorz Woźniak, Małgorzata Kraszkiewicz, Michał Gola, Michał Kalemba, Grzegorz Głowacki, Bartłomiej Tomasik, Magdalena Kocot-Kępska, Leszek Miszczyk | Radiother Oncol | 2022

Outcomes of fractionated CyberKnife radiosurgery in patients with choroidal malignant melanoma

Ceyda Baskan, Ebru Atasever Akkas, Sabite Emine Gökce, Sibel Ozdogan | Acta Oncol | 2022

2486: Correlation between Obesity and Treatment Failure Following Stereotactic Body Radiation Therapy (SBRT) for Clinically Localized Prostate Cancer

D. Conroy, T. Sholklapper, M. K. K. Lawlor, J. M. Cantalino, A. Zwart, M. J. Ayoob, M. Danner, T. Yung, B. T. Collins, S. Lei, A. Rashid, D. Kumar, S. Suy, N. Aghdam, and S. P. Collins | ASTRO | 2022