{"id":34338,"date":"2024-10-15T15:18:41","date_gmt":"2024-10-15T20:18:41","guid":{"rendered":"https:\/\/www.accuray.com\/?post_type=studies&p=34338"},"modified":"2024-10-30T17:19:48","modified_gmt":"2024-10-30T22:19:48","slug":"stereotactic-body-radiation-therapy-using-radixact-system-with-synchrony-for-nonagenarian-patient-with-lung-cancer","status":"publish","type":"studies","link":"https:\/\/www.accuray.com\/ja\/case-studies\/stereotactic-body-radiation-therapy-using-radixact-system-with-synchrony-for-nonagenarian-patient-with-lung-cancer\/","title":{"rendered":"Stereotactic Body Radiation Therapy using Radixact\u00ae System with Synchrony\u00ae for Nonagenarian Patient with Lung Cancer\u00a0"},"content":{"rendered":"\t\t
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\n\t\t\t\t\t\t\t\t\t< View All Case Studies<\/a>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tCASE STUDY | TAKARAZUKA CITY HOSPITAL\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Stereotactic Body Radiation Therapy using Radixact\u00ae System with Synchrony\u00ae for Nonagenarian Patient with Lung Cancer<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tDownload Case Study<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tFor frail patients with early-stage non-small cell lung cancer (NSCLC), where\ntreatment toxicity and risk mitigation are of paramount importance, the Radixact\u00ae\nSystem with Synchrony\u00ae Lung Tracking\u2122 with Respiratory Modeling is a promising\napproach to minimize the risk of radiation pneumonitis.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Case Challenge<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tAssuring minimal toxicity with lung stereotactic body radiation\ntherapy (SBRT) for a medically inoperable elderly patient.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Treatment Planning and Delivery:<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tBefore treatment the patient was scanned using a CT device. The\npatient was simulated supine and immobilized with a vacuum\ncushion. VOLO\u2122 planning was used to develop a TomoHelical\u2122 plan.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\t\u201cWe showed that Synchrony\ntracking SBRT with the Radixact System\nwas technically feasible even for a\npatient of very advanced age.\u201d\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Treatment Rationale<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tA woman in her 90s, who has never smoked, had an abnormality on a chest X-ray. Further tests showed a 28 mm lung nodule that raised suspicion for lung cancer. Due to her age and health concerns, surgical resection was not possible. After careful\nconsideration with a tumor board, a clinical diagnosis of NSCLC\nwas made without histopathologic confirmation. She received\nSBRT (48 Gy in 4 fractions) delivered on the Radixact\u00ae System with\nSynchrony\u00ae Lung Tracking to minimize normal lung exposure and the risk of radiation pneumonitis.\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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Facts at-a-glance<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\"Takarazuka\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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FACILITY NAME<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tTakarazuka City Hospital\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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LOCATION<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tTakarazuka, Hyogo, Japan\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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ABOUT<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tSBRT using the Radixact System with\nSynchrony Lung Tracking for an elderly\npatient with medically inoperable\nearly-stage NSCLC\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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TREATMENT SYSTEM EXPERIENCE<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tRadixact Treatment Delivery System\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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UPGRADE TECHNOLOGY SOLUTIONS<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tSynchrony\u00ae Lung Tracking\u2122 with\nRespiratory Modelling\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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CASE MIX<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tMedically inoperable early-stage\nNSCLC\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tFigure 1. Diagnostic CT and PET\/CT images prior to treatment delivery\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tFigure 2. Screen-shot of VOLO\u2122 treatment planning\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Outcomes \/ Conclusions<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tSynchrony Lung Tracking with Respiratory Modeling reduced PTV volume from 60.7cc to 32.2cc and irradiated normal lung V20Gy from 7.8% to 5.0%. Beam-on time for the treatment delivery was approximately nine minutes. During the treatment delivery, the kV imaging system detected the lung tumor without difficulty. The threshold of potential difference, which is a statistical prediction of the 3D distance error, was set at 3.5 mm. It was possible to complete treatment without major problems, although occasionally the respiratory signal pattern changed during treatment, necessitating treatment pauses. The patient tolerated treatment well. At the 1-month follow-up visit, there were no symptoms or chest X-ray findings suggestive of radiation pneumonitis. SBRT is an established definitive treatment for inoperable or high-risk operable patients with early-stage NSCLC. For such frail patients, treatment toxicity and risk mitigation are of paramount importance. Synchrony Lung Tracking with Respiratory Modeling is a promising approach as it can enable accurate tumor targeting and a reduction in irradiated normal lung volume, minimizing the risk of radiation pneumonitis.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tImportant Safety InformationMost side effects of radiotherapy, including radiotherapy delivered with Accuray systems, are mild and temporary, often involving fatigue, nausea, and skin irritation. Side effects can be severe, however, leading to pain, alterations in normal body functions\n(for example, urinary or salivary function), deterioration of quality of life, permanent injury, and even death. Side effects can occur during or shortly after radiation treatment or in the months and years following radiation. The nature and severity of side effects depend on many factors, including the size and location of the treated tumor, the treatment technique (for example, the radiation dose), and the patient\u2019s general medical condition, to name a few. For more details about the side effects of your radiation therapy, and to see if treatment with an Accuray product is right for you, ask your doctor. Accuray Incorporated as a medical device manufacturer cannot and does not recommend specific treatment approaches. Individual results may vary.\n\n

\u00a9 2023 Accuray Incorporated. All Rights Reserved. Accuray, the Accuray logo, and other trademarks are trademarks or registered trademarks of Accuray Incorporated and may not be used without permission. For more information on Accuray and its trademarks, please visit www.accuray.com\/trademarks. MKT004351\n<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

For frail patients with early-stage non-small cell lung cancer (NSCLC), where treatment toxicity and risk mitigation are of paramount importance, the Radixact\u00ae System with Synchrony\u00ae Lung Tracking\u2122 with Respiratory Modeling is a promising approach to minimize the risk of radiation pneumonitis.<\/p>\n","protected":false},"featured_media":34434,"menu_order":0,"template":"","meta":{"_acf_changed":false,"inline_featured_image":false,"_links_to":"","_links_to_target":""},"categories":[1265],"studies_products":[],"case_studies_products":[1268],"class_list":["post-34338","studies","type-studies","status-publish","has-post-thumbnail","hentry","category-tomotherapy-radixact","case_studies_products-tomotherapy-radixact"],"acf":[],"yoast_head":"\nStereotactic Body Radiation Therapy using Radixact\u00ae System with Synchrony\u00ae for Nonagenarian Patient with Lung Cancer\u00a0 - Accuray<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.accuray.com\/case-studies\/stereotactic-body-radiation-therapy-using-radixact-system-with-synchrony-for-nonagenarian-patient-with-lung-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Stereotactic Body Radiation Therapy using Radixact\u00ae System with Synchrony\u00ae for Nonagenarian Patient with Lung Cancer\u00a0\" \/>\n<meta property=\"og:description\" content=\"For frail patients with early-stage non-small cell lung cancer (NSCLC), where treatment toxicity and risk mitigation are of paramount importance, the Radixact\u00ae System with Synchrony\u00ae Lung Tracking\u2122 with Respiratory Modeling is a promising approach to minimize the risk of radiation pneumonitis.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.accuray.com\/case-studies\/stereotactic-body-radiation-therapy-using-radixact-system-with-synchrony-for-nonagenarian-patient-with-lung-cancer\/\" \/>\n<meta property=\"og:site_name\" content=\"Accuray\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/AccurayIncorporated\" \/>\n<meta property=\"article:modified_time\" content=\"2024-10-30T22:19:48+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.accuray.com\/wp-content\/uploads\/Image3.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1167\" \/>\n\t<meta property=\"og:image:height\" content=\"764\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@Accuray\" \/>\n<meta name=\"twitter:label1\" content=\"\u63a8\u5b9a\u8aad\u307f\u53d6\u308a\u6642\u9593\" \/>\n\t<meta name=\"twitter:data1\" content=\"4\u5206\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.accuray.com\/case-studies\/stereotactic-body-radiation-therapy-using-radixact-system-with-synchrony-for-nonagenarian-patient-with-lung-cancer\/\",\"url\":\"https:\/\/www.accuray.com\/case-studies\/stereotactic-body-radiation-therapy-using-radixact-system-with-synchrony-for-nonagenarian-patient-with-lung-cancer\/\",\"name\":\"Stereotactic Body Radiation Therapy using Radixact\u00ae System with Synchrony\u00ae for Nonagenarian Patient with Lung Cancer\u00a0 - 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