30 Years of Evidence

Take a moment to explore a selection of publications and conference abstracts from around the globe. Find evidence for a wide range of treatment sites including malignant and benign disease, different fractionation schedules and real-time motion synchronization techniques for the CyberKnife® and Radixact®/ TomoTherapy® platforms. We update new papers on a regular basis. See how health professionals are helping to improve patient outcomes.

Stereotactic Body Radiotherapy Boost with the CyberKnife for Locally Advanced Cervical Cancer: Dosimetric Analysis and Potential Clinical Benefits

Gao J, Xu B, Lin Y, Xu Z, Huang M, Li X, Wu X, Chen Y. | Cancers (Basel) | 2022

Ablative vs. Non-Ablative Radiotherapy in Palliating Locally Advanced Pancreatic Cancer: A Single Institution Experience and a Systematic Review of the Literature

Kamel R, Dennis K, Doody J, Pantarotto J. | Cancers (Basel) | 2023

First UK Patient Cohort Treated with Stereotactic Ablative Radiotherapy for Primary Kidney Cancer

Zarkar A, Henderson D, Carver A, Heyes G, Harrop V, Tutill S, Kilkenny J, Marshall A, Elbeltagi N, Howard H | BJUI Compass | 2023

Potential Benefit of Dose-Escalated Stereotactic Body Radiation Therapy using CyberKnife for Early-Stage Primary Lung Cancer

Watanabe S, Yamazaki H, Kimoto T, Shiomi H, Yamada K, Suzuki G | Asia Pac J Clin Oncol | 2023

Stereotactic Ablative Body Radiotherapy with w Central High Dose using CyberKnife for Metastatic Lung Tumors

Hayashi K, Suzuki O, Shiomi H, Ono H, Setoguchi A, Nakai M, Nakanishi E, Tatekawa S, Ose N, Hirata T, Tamari K, Seo Y, Funaki S, Isohashi F, Shimizu S, Shintani Y, Ogawa K | BMC Cancer | 2023

Challenges of BCLC stage C hepatocellular carcinoma: Results of a single-institutional experience on stereotactic body radiation therapy

Que J, Lin CH, Lin LC, Ho CH | Medicine (Baltimore) | 2020

Experience with Normal Breathhold Planning Scans for Radiosurgery of Moving Targets with Live Tracking

Grimm J, Naidoo SF, Yossef K, Shukla G, Scofield CJ, Searfoss AC, Zulkoski MA, Tanyi JA, Mackley HB, Mahadevan | eCollection | 2023

CyberKnife Xsight Versus Fiducial-Based Target-Tracking: A Novel 3D Dosimetric Comparison in a Dynamic Phantom

Klein TJ, Gill S, Ebert MA, Grogan G, Smith W, Alkhatib Z, Geraghty J, Scott AJD, Brown A, Rowshanfarzad P | Radiat Oncol | 2022

Large Prostate Volume Does Not Negatively Impact Health-Related Quality of Life in Patients with Prostate Cancer Treated with Ultra-hypofractionated Stereotactic Body Radiotherapy

Piotr Milecki, Anna Adamska, Anna Rucinska, Grzegorz Pałucki, Agnieszka Szumiło, Agnieszka Skrobała, Agata Jodda, Michał Michalak | J Pers Med | 2023

Stereotactic Body Radiation Therapy for Prostate Cancer: A Study Comparing 3-year Genitourinary Toxicity Between CyberKnife and Volumetric-Modulated Arc Therapy by Propensity Score Analysis

Makoto Ito, Yasuo Yoshioka, Yuuki Takase, Junji Suzuki, Hironori Takahashi, Yoshitaka Minami, Ami Sakuragi, Yukihiko Oshima, Takahito Okuda, Kojiro Suzuki | Radiat Oncol | 2023

Robotic Stereotactic Body Radiotherapy for Localized Prostate Cancer: Final Analysis of the German Hypostat Trial

David Krug, Detlef Imhoff, Alfred Haidenberger, Nicole Heßler, Jane Schäfer, Stefan Huttenlocher, Georgios Chatzikonstantinou, Christoph Fürweger, Ulla Ramm, Inke R König, Felix Chun, Michael Staehler, Claus Rödel, Alexander Muacevic, Reinhard Vonthein, Jürgen Dunst, Oliver Blanck | Strahlenther Onkol | 2023

Survival and Prognostic Factors of Ultra-Central Tumors Treated with Stereotactic Body Radiotherapy

Salvestrini V, Duijm M, Loi M, Nuyttens JJ | Cancers (Basel) | 2022

Robotic CyberKnife Radiosurgery for the Treatment of Choroidal and Ciliary Body Melanoma

Liegl R, Schmelter V, Fuerweger C, Ehret F, Priglinger S, Muacevic A, Foerster P | Am J Ophthalmol | 2023

Outcomes of fractionated CyberKnife radiosurgery in patients with choroidal malignant melanoma

Ceyda Baskan, Ebru Atasever Akkas, Sabite Emine Gökce, Sibel Ozdogan | Acta Oncol | 2022

Potential Clinical Significance of Overall Targeting Accuracy and Motion Management in the Treatment of Tumors That Move With Respiration: Lessons Learnt From a Quarter Century of Stereotactic Body Radiotherapy From Dose Response Models – PubMed (nih.gov)

Mahadevan A, Emami B, Grimm J, Kleinberg LR, Redmond KJ, Welsh JS, Rostock R, Kemmerer E, Forster KM, Stanford J, Shah S, Asbell SO, LaCouture TA, Scofield C, Butterwick I, Xue J, Muacevic A, Adler JR | Front Oncol | 2021

CyberKnife Versus Four-Dimensional Computed Tomography-Guided Stereotactic Body Radiation Therapy in the Treatment of Lung Cancer: A Case Report

Tang L, Yao L, Li G. | Cureus Competition | 2025

Artificial Intelligence (AI)-Driven Adaptive Motion Management in Helical and Robotic Radiotherapy: Innovations, Challenges, and Future Directions

Panda DK, Das SR, Kumar S. | Cureus Competition | 2025

A Quality Control Procedure for Single Fiducial Tracking of Lung Lesions.

Descovich M, Lau E, Hasse K, Gottschalk A. | Cureus Competition | 2025

Salvage Radiosurgery After Brachytherapy for Locally Recurrent Prostate Cancer With Real-Time Adaptive Motion Management Using Previously Implanted Brachytherapy Seeds as Fiducial Markers

Yu JB, Grew DJ, Singh C, Sculley E, Jones A, Munbodh R. | Cureus Competition | 2025

CyberKnife Staged Radiotherapy for Elderly Patients With Poorly Differentiated Lung Adenocarcinoma: A Case Report and Dosimetric Analysis

Gu S, Liu X, Du L, Ju Z, Wang H, Sun J, Dai X. | Cureus Competition | 2025

Excellent Outcomes With Stereotactic Body Radiotherapy in an Elderly Patient With Locally Progressive Immunotherapy-Resistant Renal Cell Carcinoma

Miriam Torrisi, Laura Giannini, Roberta Tummineri, Chiara Lucrezia Deantoni, Andrei Fodor | Cureus Competition | 2025

Robotic Stereotactic Body Radiation Therapy for High-Risk Prostate Cancer: The Georgetown University Experience

Vaibhav Sharma, Tim Kearney, Zach Lee, Padraig Brennan Pilkington, Marielle Fis Loperena, Malika Danner, Alan L. Zwart, Deepak Kumar, Brian Collins, Michael Carrasquilla, Suy Simeng, Sean Collins | Cureus Competition | 2025