Découvrez ClearRT™* pour le système Radixact®
Le système d’imagerie kV hélicoïdale haute fidélité qui permet :
Découvrez le système Radixact®
Le système Radixact, la dernière génération de la plateforme TomoTherapy® est un système de radiothérapie à modulation d’intensité, guidé par imagerie 3D qui permet de créer des traitements personnalisés pour un grand nombre d’indications, indépendamment de la complexité ou du nombre de tumeurs.
Un modulateur binaire et un mode d’administration hélicoïdale uniques
- Les doses sont sculptées pour cibler la tumeur précisément et éviter les tissus sains
- Moins de rayons sur les tissus sains, ce sont moins d’effets secondaires
- Plusieurs zones peuvent être ciblées en un seul traitement
Un guidage par imagerie 3D quotidien
- L’imagerie de TomoTherapy® permet de contrôler les doses délivrées avant chaque séance
- Le traitement peut être réadapté sur mesure conformément aux changements anatomiques,
si nécessaire - Ainsi, le traitement initialement prescrit est respecté
Un système de planification des traitements en temps réel flexible et performant
- Nouvel algorithme qui donne plus de flexibilité, rapidité et efficacité
- permet une analyse quantitative des doses délivrées au jour le jour
à n’importe quel étape du traitement
Le système Radixact permet aux médecins de traiter un large éventail de cancer, des cas traités en routine aux cas les plus complexes, avec une efficacité de traitement accrue. Il est capable de traiter :
- les tumeurs de petite ou de grande taille ;
- les tumeurs multiples, siégeant dans différentes parties du corps, au cours d’une même séance ou d’un même traitement ;
- toutes les indications de la radiothérapie conventionnelle : cancers du cerveau, du sein, de la tête et du cou, du poumon, de la prostate, du rectum, de la colonne vertébrale, pédiatriques.
Plus de 20 ans d’évidence clinique
SRS Treatment
TOMOTHERAPY BRAIN METS
Publications
- Bruni A, Gaito S, Ciarmatori A et al. Radiosurgery Using Tomotherapy for Patients with Brain Oligo-metastasis: A Retrospective Analysis on Feasibility and Tolerance. Anticancer Res. 2015 Dec;35(12):6805-12
- Barra A, Agostinello A, Vagge S et al. Radiosurgery with Helical Tomotherapy: Outcomes for Patients with One or Multifocal Brain Metastasis. Technol Cancer Res Treat. 2015 Dec;14(6):693-9
- Koide Y, Tomita N, Adachi S et al. Retrospective analysis of hypofractionated stereotactic radiotherapyfor tumors larger than 2 cm. Nagoya J Med Sci. 2019 Aug;81(3):397-406.
- Saw CB, Gillette C, Peters CA et al. Clinical implementation of radiosurgery using the Helical TomoTherapy unit. Med Dosim. 2018 Autumn;43(3):284-29
- Murai T, Hayashi A, Manabe Y, Sugie C, Takaoka T, Yanagi T, Oguri T, Matsuo M, Mori Y, Shibamoto Y. Efficacy of stereotactic radiotherapy for brain metastases using dynamic jaws technology in the helical tomotherapy system. Br J Radiol. 2016 Oct;89(1066):20160374.
ASTRO/ESTRO 2020 Posters
SBRT Treatment
TOMOTHERAPY LUNG
Publications
- Figlia V, Mazzola R, Cuccia F, Alongi F, Mortellaro G, Cespuglio D, Cucchiara T, Iacoviello G, Valenti V, Molino M, Verderame F, Matranga D, Casto AL, Ferrera G. Hypo-fractionated stereotactic radiation therapy for lung malignancies by means of helical tomotherapy: report of feasibility by a single-center experience. Radiol Med. 2018 Jun;123(6):406-414.
- Scotti V, Bruni A, Francolini G, Perna M, Vasilyeva P, Loi M, Simontacchi G, Viggiano D, Lanfranchi B, Gonfiotti A, Topulli J, Olmetto E, Maragna V, Ferrari K, Bonti V, Comin C, Balduzzi S, D’Amico R, Lohr F, Voltolini L, Livi L. Stereotactic Ablative Radiotherapy as an Alternative to Lobectomy in Patients With Medically Operable Stage I NSCLC: A Retrospective, Multicenter Analysis. Clin Lung Cancer. 2019 Jan;20(1):e53-e61.
ASTRO/ESTRO 2020 Posters
- Poster session PV 02, poster 2576 Lung SBRT Using Helical Tomotherapy: Dosimetric and Delivery Comparison of Dynamic Jaw and Fixed Jaw [plan.core-apps.com]
- Poster session PV 02, poster 2711 Going “ITV-Free”: First-in-Clinic Experience with a Real Time Motion Tracking Technique for Lung SBRT Delivery [plan.core-apps.com]
TOMOTHERAPY MESOTHELIOMA
Publications
- Hong JH, Lee HC, Choi KH, Moon SW, Kim KS, Hong SH, Hong JY, Kim YS. Preliminary results of entire pleural intensity-modulated radiotherapy in a neoadjuvant setting for resectable malignant mesothelioma. Radiat Oncol J. 2019 Jun;37(2):101-109.
- Parisi E, Romeo A, Sarnelli A, Ghigi G, Bellia SR, Neri E, Micheletti S, Dipalma B, Arpa D, Furini G, Burgio MA, Genestreti G, Gurioli C, Sanna S, Bovolato P, Rea F, Storme G, Scarpi E, Arienti C, Tesei A, Polico R. High dose irradiation after pleurectomy/decortication or biopsy for pleural mesothelioma treatment. Cancer Radiother. 2017 Dec;21(8):766-773.
TOMOTHERAPY LIVER
Publications
- Jung J, Kong M, Hong SE. Conventional fractionated helical tomotherapy for patients with small to medium hepatocellular carcinomas without portal vein tumor thrombosis. Onco Targets Ther. 2014 Sep 26;7:1769-75.
- Yoon HI, Lee IJ, Han KH, Seong J. Improved oncologic outcomes with image-guided intensity-modulated radiation therapy using helical tomotherapy in locally advanced hepatocellular carcinoma. J Cancer Res Clin Oncol. 2014 Sep;140(9):1595-605.
- Kim JY, Yoo EJ, Jang JW, Kwon JH, Kim KJ, Kay CS. Hypofractionated radiotheapy using helical tomotherapy for advanced hepatocellular carcinoma with portal vein tumor thrombosis. Radiat Oncol. 2013 Jan 16;8:15.
IG-IMRT Treatment
TOMOTHERAPY INTRACRANIAL
Publications
- Boulle G, Bracci S, Hitchcock K, Jacob J, Clausse E, Halley A, Belghith B, Kamsu Kom L, Canova CH, Bielle F, Chevalier A, Peyre M, Mazeron JJ, Maingon P, Feuvret L. Treatment of grade II-III intracranial meningioma with helical tomotherapy. J Clin Neurosci. 2019 Jan;59:190-196.
TOMOTHERAPY HEAD & NECK
Publications
- T Liu Z, Xu C, Jiang R, Liu G, Liu Q, Zhou J, Liu F, Yao J, Wang S, Jiang W. Treatment of Locally Advanced Nasopharyngeal Carcinoma by Helical Tomotherapy: An Observational, Prospective Analysis. Transl Oncol. 2019 May;12(5):757-763.
- Chitapanarux I, Nobnop W, Sripan P, Chumachote A, Tharavichitkul E, Chakrabandhu S, Klunklin P, Onchan W, Jia-Mahasap B, Janlaor S, Kayan P, Traisathit P, Van Gestel D. The Outcome of the First 100 Nasopharyngeal Cancer Patients in Thailand Treated by Helical Tomotherapy. Radiol Oncol. 2017 Apr 21;51(3):351-356.
- Du L, Zhang XX, Feng LC, Qu BL, Chen J, Yang J, Liu HX, Xu SP, Xie CB, Ma L. Propensity score matching analysis of a phase II study on simultaneous modulated accelerated radiation therapy using helical tomotherapy for nasopharyngeal carcinomas. BMC Cancer. 2017 Aug 29;17(1):582.
- Du L, Zhang XX, Feng LC, Chen J, Yang J, Liu HX, Xu SP, Xie CB, Ma L. Treatment of nasopharyngeal carcinoma using simultaneous modulated accelerated radiation therapy via helical tomotherapy: a phase II study. Radiol Oncol. 2016 Feb 7;50(2):218-25.
- Zhang X, Du L, Zhao F, Wang Q, Yang S, Ma L. A Phase II Clinical Trial of Concurrent Helical Tomotherapy plus Cetuximab Followed by Adjuvant Chemotherapy with Cisplatin and Docetaxel for Locally Advanced Nasopharyngeal Carcinoma. Int J Biol Sci. 2016 Feb 12;12(4):446-53.
- Moroney LB, Helios J, Ward EC, Crombie J, Pelecanos A, Burns CL, Spurgin AL, Blake C, Kenny L, Chua B, Hughes BGM. Helical intensity-modulated radiotherapy with concurrent chemotherapy for oropharyngeal squamous cell carcinoma: A prospective investigation of acute swallowing and toxicity patterns. Head Neck. 2018 Sep;40(9):1955-1966.
- Bibault JE, Dussart S, Pommier P, Morelle M, Huguet M, Boisselier P, Coche-Dequeant B, Alfonsi M, Bardet E, Rives M, Calugaru V, Chajon E, Noel G, Mecellem H, Servagi Vernat S, Perrier L, Giraud P. Clinical Outcomes of Several IMRT Techniques for Patients With Head and Neck Cancer: A Propensity Score-Weighted Analysis. Int J Radiat Oncol Biol Phys. 2017 Nov 15;99(4):929-937.
- Kimura K, Kodaira T, Tomita N, Tachibana H, Makita C, Yoshida M, Nishikawa D, Hirakawa H, Suzuki H, Hanai N, Hasegawa Y. Clinical results of definitive intensity-modulated radiation therapy for oropharyngeal cancer: retrospective analysis of treatment efficacy and safety. Jpn J Clin Oncol. 2016 Jan;46(1):78-85.
- Van Gestel D, Van den Weyngaert D, De Kerf G, De Ost B, Vanderveken O, Van Laer C, Specenier P, Geussens Y, Wouters K, Meulemans E, Cheung KJ, Grégoire V, Vermorken JB. Helical tomotherapy in head and neck cancer: a European single-center experience. Oncologist. 2015 Mar;20(3):279-90.
Videos
- The Outcome of the First 100 Nasopharyngeal Cancer Patients in Thailand Treated by Helical TomoTherapy®. Imjai Chitapanarux M.D., Chiang Mai University, Thailand.
- Clinical Outcomes of Several IMRT Techniques for Patients With Head and Neck Cancer: A Propensity Score-Weighted Analysis. Jean-Emmanuel Bibault, M.D., MSc Georges-Pompidou European Hospital, France.
- Impact of Postoperative Daily Image-Guided Intensity-Modulated Radiotherapy on Overall and Local Progression-Free Survival in Patients with Oral Cavity Cancer. Pei-Wei Shueng, MD, Far Eastern Memorial Hospital, Taiwan.
TOMOTHERAPY BREAST
Publications
- De Paula U, D’Angelilo AM, Andrulli AD et al. Long-Term Outcomes of Once Daily Accelerated Partial Breast Irradiation with Tomotherapy: Results of a Phase II Trial.Int J Radiat Oncol Biol Phys. Article in Press
- Joseph K, Vos LJ, Gabos Z, Pervez N, Chafe S, Tankel K, Warkentin H, Ghosh S, Amanie J, Powell K, Polkosnik LA, Horsman S, MacKenzie M, Sabri S, Parliament MB, Mackey J, Abdulkarim B. Skin Toxicity in Early Breast Cancer Patients Treated with Field-In-Field Breast Intensity-Modulated Radiotherapy versus Helical Inverse Breast Intensity-Modulated Radiotherapy: Results of a Phase III Randomised Controlled Trial. Clin Oncol (R Coll Radiol). 2020 Jul 22:S0936-6555(20)30287-9.
- Chitapanarux I, Nobnop W, Tippanya D, Sripan P, Chakrabandhu S, Klunklin P, Onchan W, Jia-Mahasap B, Tharavichitkul E. Clinical outcomes and dosimetric study of hypofractionated Helical TomoTherapy in breast cancer patients. PLoS One. 2019 Jan 31;14(1):e0211578.
- Arsene-Henry A, Foy JP, Robilliard M, Xu HP, Bazire L, Peurien D, Poortmans P, Fourquet A, Kirova YM. The use of helical tomotherapy in the treatment of early stage breast cancer: indications, tolerance, efficacy-a single center experience. Oncotarget. 2018 May 4;9(34):23608-23619.
- Orecchia R, Rojas DP, Cattani F, Ricotti R, Santoro L, Morra A, Cambria R, Luraschi R, Dicuonzo S, Ronchi S, Surgo A, Dell’ Acqua V, Veronesi P, De Lorenzi F, Fodor C, Leonardi MC, Jereczek-Fossa BA. Hypofractionated postmastectomy radiotherapy with helical tomotherapy in patients with immediate breast reconstruction: dosimetric results and acute/intermediate toxicity evaluation. Med Oncol. 2018 Feb 13;35(3):39.
- Thery L, Arsene-Henry A, Carroll S, Peurien D, Bazire L, Robilliard M, Fourquet A, Kirova YM. Use of helical tomotherapy in locally advanced and/or metastatic breast cancer for locoregional treatment. Br J Radiol. 2018 May;91(1085):20170822.
- Mathieu D, Bedwani S, Mascolo-Fortin J, Côté N, Bernard AA, Roberge D, Yassa M, Bahig H, Vu T. Cardiac Sparing with Personalized Treatment Planning for Early-stage Left Breast Cancer. 2020 Mar 12;12(3):e7247.
- Joseph K, Vos LJ, Gabos Z, Pervez N, Chafe S, Tankel K, Warkentin H, Ghosh S, Amanie J, Powell K, Polkosnik LA, Horsman S, MacKenzie M, Sabri S, Parliament MB, Mackey J, Abdulkarim B. Skin Toxicity in Early Breast Cancer Patients Treated with Field-In-Field Breast Intensity-Modulated Radiotherapy versus Helical Inverse Breast Intensity-Modulated Radiotherapy: Results of a Phase III Randomised Controlled Trial. Clin Oncol (R Coll Radiol). 2020 Jul 22:S0936-6555(20)30287-9.
Videos
- TomoTherapy for Breast Cancer in a Clinical Setting. Samantha Dicuonzo M.D. & Raffaella Cambria M.Sc., European Institute of Oncology, Milan, Italy.
- Clinical Outcomes and Dosimetric Study of Hypofractionated Helical TomoTherapy® in Breast Cancer Patients. Imjai Chitapanarux M.D. Chiang Mai University, Thailand.
- A Comprehensive Radiotherapy Strategy for Managing Breast Cancer. Rupesh Kotecha, M.D., Miami Cancer Institute, Miami FL, USA.
- Breast Cancer: Your Challenges Today – Our Solutions for Tomorrow. Nathan Corradini, MS, DABR, SSRMP, Clinica Luganese, Lugano, Switzerland, Carole Massabeau, M.D., Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France, Jennifer R. Bellon, M.D. Dana-Farber Cancer Institute, Boston, MA, USA.
- Benefits of TomoDirect™ to Treat Breast Cancer. Nathan Corradini, MS, DABR, SSRMP | Clinica Luganese – Lugano, Switzerland.
- Using the Tomotherapy® System for Whole Breast Irradiation in the Community Clinic Setting. Robert A. Harris, M.D., Gamma West, Layton, UT, USA.
ASTRO/ESTRO 2020 Posters
- Breast poster session (PV 01) – Poster 2036 Long-Term Outcomes of Once Daily Accelerated Partial Breast Irradiation with TomoTherapy: Phase II Trial Results on 338 Women Treated at a Single Institution [plan.core-apps.com]
- Breast poster session (PV 01) – Poster 2071 Long-Term Risks of Secondary Cancer for Various Whole Breast Irradiation Techniques, Including Helical IMRT [plan.core-apps.com]
TOMOTHERAPY LUNG
Publications
- Vekens K, Verbanck S, Collen C, Storme G, Barbé K, De Ridder M, Vanderhelst E. Pulmonary function changes following helical tomotherapy in patients with inoperable, locally advanced non-small cell lung cancer. Strahlenther Onkol. 2020 Feb;196(2):142-150.
TOMOTHERAPY MESOTHELIOMA
Publications
- Harrabi SB, Koerber SA, Adeberg S, Katayama S, Herfarth K, Debus J, Sterzing F. Malignant pleural mesothelioma – Pleural cavity irradiation after decortication with helical tomotherapy. Rep Pract Oncol Radiother. 2017 Sep-Oct;22(5):402-407.
- Kishan AU, Cameron RB, Wang PC, Alexander S, Qi SX, Low DA, Kupelian PA, Steinberg ML, Lee JM, Selch MT, Lee P. Tomotherapy improves local control and changes failure patterns in locally advanced malignant pleural mesothelioma. Pract Radiat Oncol. 2015 Nov-Dec;5(6):366-73.
TOMOTHERAPY PROSTATE
Publications
- Macias VA, Barrera-Mellado I. Ultra-hypofractionated radiation therapy for unfavourable intermediate-risk and high-risk prostate cancer is safe and effective: 5-year outcomes of a phase II trial. BJU Int. 2019 Oct 15. doi: 10.1111/bju.14925.
- Di Muzio NG, Fodor A, Noris Chiorda B, Broggi S, Mangili P, Valdagni R, Dell’Oca I, Pasetti M, Deantoni CL, Chiara A, Berardi G, Briganti A, Calandrino R, Cozzarini C, Fiorino C. Moderate Hypofractionation with Simultaneous Integrated Boost in Prostate Cancer: Long-term Results of a Phase I-II Study. Clin Oncol (R Coll Radiol). 2016 Aug;28(8):490-500.
- Tomita N, Soga N, Ogura Y, Hayashi N, Kageyama T, Ito M, Koide Y, Yoshida M, Kimura K, Makita C, Tachibana H, Kodaira T. High-dose radiotherapy with helical tomotherapy and long-term androgen deprivation therapy for prostate cancer: 5-year outcomes. J Cancer Res Clin Oncol. 2016 Jul;142(7):1609-19.
- Yamazaki H, Masui K, Suzuki G, Nakamura S, Shimizu D, Nishikawa T, Okabe H, Yoshida K, Kotsuma T, Tanaka E, Otani K, Yoshioka Y, Ogawa K. High-Dose-Rate Brachytherapy Monotherapy versus Image-Guided Intensity-Modulated Radiotherapy with Helical Tomotherapy for Patients with Localized Prostate Cancer. Cancers (Basel). 2018 Sep 10;10(9):322.
Videos
- Safe and Effective Stereotactic Body Radiation Therapy (SBRT) for High-Risk Prostate Cancer Patients: 4-year Outcomes of a Phase II Trial. Victor Macias Hernandez, M.D., Ph.D. Salamanca University Hospital; Valladolid University Hospital,
TOMOTHERAPY RECTAL CANCER
Publications
- De Bari B, Franzetti-Pellanda A, Saidi A, Biggiogero M, Hahnloser D, Montemurro M, Bourhis J, Zeverino M, Ozsahin M. Neoadjuvant chemoradiotherapy delivered with helical tomotherapy under daily image guidance for rectal cancer patients: efficacy and safety in a large, multi-institutional series. J Cancer Res Clin Oncol. 2019 Apr;145(4):1075-1084.
- Zhao J, Liu X, Wang W, Hu K, Zhang F, Hou X, Meng Q. Concomitant dose escalation with image-guided Tomotherapy in locally advanced mid-low rectal cancer: a single-center study. Cancer Manag Res. 2019 Feb 15;11:1579-1586.
- Huang CM, Huang MY, Tsai HL, Huang CW, Ma CJ, Lin CH, Huang CJ, Wang JY. A retrospective comparison of outcome and toxicity of preoperative image-guided intensity-modulated radiotherapy versus conventional pelvic radiotherapy for locally advanced rectal carcinoma. J Radiat Res. 2017 Mar 1;58(2):247-259.
Videos
- Role of the TomoTherapy® System in the Treatment of Rectal Cancer. Berardino De Bari M.D., University Hospital of Besançon, France.
- TomoTherapy® for Advanced Rectal Cancer. Xiaoliang Liu, M.D., Peking Union Medical College Hospital, Beijing, China.
TOMOTHERAPY ANAL CANCER
Publications
- Klausner G, Blais E, Jumeau R, Biau J, de Meric de Bellefon M, Ozsahin M, Zilli T, Miralbell R, Thariat J, Troussier I. Management of locally advanced anal canal carcinoma with intensity-modulated radiotherapy and concurrent chemotherapy. Med Oncol. 2018 Aug 20;35(10):134.
- De Bari B, Lestrade L, Franzetti-Pellanda A, Jumeau R, Biggiogero M, Kountouri M, Matzinger O, Miralbell R, Bourhis J, Ozsahin M, Zilli T. Modern intensity-modulated radiotherapy with image guidance allows low toxicity rates and good local control in chemoradiotherapy for anal cancer patients. J Cancer Res Clin Oncol. 2018 Apr;144(4):781-789.
- Joseph K, Vos LJ, Warkentin H, Paulson K, Polkosnik LA, Usmani N, Tankel K, Severin D, Nijjar T, Schiller D, Wong C, Ghosh S, Mulder K, Field C. Patient reported quality of life after helical IMRT based concurrent chemoradiation of locally advanced anal cancer. Radiother Oncol. 2016 Aug;120(2):228-33.
- Koerber SA, Slynko A, Haefner MF, Krug D, Schoneweg C, Kessel K, Kopp-Schneider A, Herfarth K, Debus J, Sterzing F. Efficacy and toxicity of chemoradiation in patients with anal cancer–a retrospective analysis. Radiat Oncol. 2014 May 13;9:113.
TOMOTHERAPY BLADDER
Publications
- Murthy V, Gupta P, Baruah K, Krishnatry R, Joshi A, Prabhash K, Noronha V, Menon S, Pal M, Prakash G, Bakshi G. Adaptive Radiotherapy for Carcinoma of the Urinary Bladder: Long-term Outcomes With Dose Escalation. Clin Oncol (R Coll Radiol). 2019 Sep;31(9):646-652.
TOMOTHERAPY SARCOMA
Publications
- Salfelder MA, Kessel KA, Thiel U, Burdach S, Kampfer S, Combs SE. Prospective evaluation of multitarget treatment of pediatric patients with helical intensity-modulated radiotherapy. Strahlenther Onkol. 2020 Aug 3.
- Peeken JC, Knie C, Kessel KA, Habermehl D, Kampfer S, Dapper H, Devecka M, von Eisenhart-Rothe R, Specht K, Weichert W, Wörtler K, Knebel C, Wilkens JJ, Combs SE. Neoadjuvant image-guided helical intensity modulated radiotherapy of extremity sarcomas – a single center experience. Radiat Oncol. 2019 Jan 9;14(1):2.
Long Fields Treatment
TOMOTHERAPY TOTAL BODY IRRADIATION
Publications
- Wilhelm-Buchstab T, Leitzen C, Schmeel LC, Simon B, Koch D, Schmeel FC, Schoroth F, Garbe S, Röhner F, Wolf D, Schüller H, Schild HH, Müdder T. Total body irradiation: Significant dose sparing of lung tissue achievable by helical tomotherapy. Z Med Phys. 2020 Feb;30(1):17-23.
- Paix A, Antoni D, Waissi W, Ledoux MP, Bilger K, Fornecker L, Noel G. Total body irradiation in allogeneic bone marrow transplantation conditioning regimens: A review. Crit Rev Oncol Hematol. 2018 Mar;123:138-148.
- Sarradin V, Simon L, Huynh A, Gilhodes J, Filleron T, Izar F. Total body irradiation using Helical Tomotherapy®: Treatment technique, dosimetric results and initial clinical experience. Cancer Radiother. 2018 Feb;22(1):17-24.
- Gruen A, Ebell W, Wlodarczyk W, Neumann O, Kuehl JS, Stromberger C, Budach V, Marnitz S. Total Body Irradiation (TBI) using Helical Tomotherapy in children and young adults undergoing stem cell transplantation. Radiat Oncol. 2013 Apr 15;8:92.
- Chao M, Penagaricano J, Yan Y, Moros EG, Corry P, Ratanatharathorn V. Voxel-based dose reconstruction for total body irradiation with helical tomotherapy. Int J Radiat Oncol Biol Phys. 2012 Apr 1;82(5):1575-83.
Videos
- Russian Experience of using Helical TomoTherapy for Total Body Irradiation in Wide Heterogenic Cohort of 262 Pediatric Patients with Hematological Malignancies. Daria Kobyzeva M.D. & Anna Loginova M.S, Dmitry Rogachev National Medical Research Center, Moscow, Russia.
TOMOTHERAPY TOTAL MARROW IRRADIATION
Publications
- Zuro D, Vagge S, Broggi S, Agostinelli S, Takahashi Y, Brooks J, Leszcynska P, Liu A, Zucchetti C, Saldi S, Han C, Cattaneo M, Giebel S, Mahe MA, Sanchez JF, Alaei P, Anna C, Dusenbery K, Pierini A, Storme G, Aristei C, Wong JYC, Hui S. Multi-institutional evaluation of MVCT guided patient registration and dosimetric precision in total marrow irradiation: A global health initiative by the international consortium of total marrow irradiation. Radiother Oncol. 2019 Dec;141:275-282.
- Haraldsson A, Engellau J, Lenhoff S, Engelholm S, Bäck S, Engström PE. Implementing safe and robust Total Marrow Irradiation using Helical Tomotherapy – A practical guide. Phys Med. 2019 Apr;60:162-167. D
- Paix A, Antoni D, Waissi W, Ledoux MP, Bilger K, Fornecker L, Noel G. Total body irradiation in allogeneic bone marrow transplantation conditioning regimens: A review. Crit Rev Oncol Hematol. 2018 Mar;123:138-148.
- Takahashi Y, Vagge S, Agostinelli S, Han E, Matulewicz L, Schubert K, Chityala R, Ratanatharathorn V, Tournel K, Penagaricano JA, Florian S, Mahe MA, Verneris MR, Weisdorf DJ, Corvo R, Dusenbery KE, Storme G, Hui SK. Multi-institutional feasibility study of a fast patient localization method in total marrow irradiation with helical tomotherapy: a global health initiative by the international consortium of total marrow irradiation. Int J Radiat Oncol Biol Phys. 2015 Jan 1;91(1):30-8.
- Kim JH, Stein A, Tsai N, Schultheiss TE, Palmer J, Liu A, Rosenthal J, Forman SJ, Wong JY. Extramedullary relapse following total marrow and lymphoid irradiation in patients undergoing allogeneic hematopoietic cell transplantation. Int J Radiat Oncol Biol Phys. 2014 May 1;89(1):75-81.
- Takahashi Y, Hui SK. Fast, simple, and informative patient-specific dose verification method for intensity modulated total marrow irradiation with helical tomotherapy. Radiat Oncol. 2014 Jan 25;9:34.
Videos
- From TBI to TMI for Advanced Onco-Hematological Diseases. Stefano Vagge M.D. Ph.D. IRCCS Policlinico San Martino, Genova, Italy.
- Total Marrow Irradiation with TomoTherapy®: Redefining the Role of Radiation Therapy in Hematopoietic Cell Transplantation. Jeffrey Wong M. D. & An Liu Ph.D., City of Hope, Duarte, CA, USA.
ASTRO/ESTRO 2020 Posters
TOTAL SKIN IRRADIATION
Publications
- Haraldsson A, Engleson J, Bäck SÅJ, Engelholm S, Engström PE. A Helical tomotherapy as a robust low-dose treatment alternative for total skin irradiation. J Appl Clin Med Phys. 2019 May;20(5):44-54.
- Hsieh CH, Tien HJ, Yu YB, Wu YH, Shueng PW, Lu YF, Wang SY, Wang LY. Simultaneous integrated boost with helical arc radiotherapy of total skin (HEARTS) to treat cutaneous manifestations of advanced, therapy-refractory cutaneous lymphoma and leukemia – dosimetry comparison of different regimens and clinical application. Radiat Oncol. 2019 Jan 28;14(1):17.
- Hsieh CH, Shueng PW, Lin SC, Tien HJ, Shiau AC, Chou YH, Wu MH, Wang JY, Chen CK, Chen YJ. Helical irradiation of the total skin with dose painting to replace total skin electron beam therapy for therapy-refractory cutaneous CD4+ T-cell lymphoma. Biomed Res Int. 2013;2013:717589.
TOMOTHERAPY PEDIATRICS
Publications
- Salfelder MA, Kessel KA, Thiel U, Burdach S, Kampfer S, Combs SE. Prospective evaluation of multitarget treatment of pediatric patients with helical intensity-modulated radiotherapy. Strahlenther Onkol. 2020 Aug 3.
- Chen GY, Cheng JC, Chen YH, Lu MY, Chang HH, Yang YL, Jou ST, Hsu WM, Kuo SH. Local Control and Clinical Outcome of High-risk Pediatric Neuroblastoma Patients After Receiving Multimodality Treatment and Helical Tomotherapy. Anticancer Res. 2019 Apr;39(4):2207-2215.
- Scobioala S, Parfitt R, Matulat P, Kittel C, Ebrahimi F, Wolters H, Am Zehnhoff-Dinnesen A, Eich HT. Impact of radiation technique, radiation fraction dose, and total cisplatin dose on hearing : Retrospective analysis of 29 medulloblastoma patients. Strahlenther Onkol. 2017 Nov;193(11):910-920.
- Schiopu SR, Habl G, Häfner M, Katayama S, Herfarth K, Debus J, Sterzing F. Craniospinal irradiation using helical tomotherapy for central nervous system tumors. J Radiat Res. 2017 Mar 1;58(2):238-246.
- Peñagarícano J, Moros E, Corry P, Saylors R, Ratanatharathorn V. Pediatric craniospinal axis irradiation with helical tomotherapy: patient outcome and lack of acute pulmonary toxicity. Int J Radiat Oncol Biol Phys. 2009 Nov 15;75(4):1155-61.
- Zhang X, Ma K, Wang J, Wu W, Ma L, Huang D. A prospective evaluation of the combined helical tomotherapy and chemotherapy in pediatric patients with unresectable rhabdomyosarcoma of the temporal bone. Cell Biochem Biophys. 2014 Sep;70(1):103-8.
Videos/Slides
- Russian Experience of using Helical TomoTherapy for Total Body Irradiation in Wide Heterogenic Cohort of 262 Pediatric Patients with Hematological Malignancies. Daria Kobyzeva M.D. & Anna Loginova M.S, Dmitry Rogachev National Medical Research Center, Moscow, Russia.
- What Does the TomoTherapy® System Bring to Pediatric Treatment Challenges? Anne Laprie, M.D., Ph.D. – IUCT Oncopole, Toulouse, France.
- VLADI: An alternative to anesthesia in radiotherapy treatments. Ana Roma Calçarão, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
Moving Targets Treatment
MOTION SYNCHRONIZATION ON RADIXACT
Publications
- Ferris WS, Culberson WS. Technical note: Patient dose from kilovoltage radiographs during motion-synchronized treatments on radixact. Med Phys. 2020 Sep 18.
- Ferris WS, Kissick MW, Bayouth JE, Culberson WS, Smilowitz JB. Evaluation of radixact motion synchrony for 3D respiratory motion: Modeling accuracy and dosimetric fidelity. J Appl Clin Med Phys. 2020 Sep;21(9):96-106.
- Chen GP, Tai A, Keiper TD, Lim S, Li XA. Technical Note: Comprehensive performance tests of the first clinical real-time motion tracking and compensation system using MLC and jaws. Med. Phys. 47 (7), July 2020.
- Price A, Chen J, Chao E, Schnarr E, Schreiber E, Lu L, Cox A, Chang S, Jian J. Compensation of intrafractional motion for lung stereotactic body radiotherapy (SBRT) on helical TomoTherapy. Phys. Eng. Express 2019;5:025043.
- Chao EH, Lucas D, Schnarr E. Evaluation of TomoTherapy dose calculations with intrafractional motion and motion compensation. Med Phys. 2018 Jan;45(1):18-28.
- Schnarr E, Beneke M, Casey D, Chao E, Chappelow J, Cox A, Henderson D, Jordan P, Lessard E, Lucas D, Myronenko A, Mauer C. Feasibility of real-time motion management with helical tomotherapy. Med Phys. 2018 Apr;45(4):1329-1337.
Videos
- Comprehensive Performance Tests of the First Clinical Real-Time Motion Tracking and Compensation System Using MLC and Jaws. Guang-Pei Chen Ph.D., Medical College of Wisconsin, Milwaukee, WI, USA.
- Dynamic Tracking and Motion Correction: Over 15 Years of Accuray Leadership featuring QA Testing of Motion Tracking with Synchrony® Allen Li, PhD, DABMP, FAAPM, Medical College of Wisconsin, Milwaukee, WI, USA.
- Validating Synchrony® on the Radixact® System for Respiratory Motion. John E. Bayouth, Ph.D, UW-Madison School of Medicine and Public Health, Madison, WI, USA.
ASTRO/ESTRO 2020 Posters
- Poster session PV 02, poster 2575 Clinical Implementation of Real-time Motion Tracking with Jaws and MLC during Helical Tomotherapy Delivery [plan.core-apps.com]
- Poster session PV 02, poster 2711 Going “ITV-Free”: First-in-Clinic Experience with a Real Time Motion Tracking Technique for Lung SBRT Delivery [plan.core-apps.com]
ClearRT™ Treatment
Patient #1 : Cervical Cancer Treated with ClearRT™ Helical kVCT Imaging on the Radixact® System**
Patient #2: Prostate Cancer Treated with ClearRT™ Helical kVCT Imaging on the Radixact® System**
Patient #3 : Lung Case Treated with ClearRT™ Helical kVCT Imaging on the Radixact® System**
Patient #4 : Female Pelvis Case Treated with ClearRT™ Helical kVCT Imaging on the Radixact® System**
Bénéficiez d’une clarté optimale avec ClearRT™
Le système d’imagerie hélicoïdale kVCT ClearRT™* permet aux cliniciens d’obtenir des images haute fidélité d’une clarté optimale pour la planification et l’administration de traitement par radiothérapie, au service d’une observation plus détaillée, d’une analyse plus approfondie et d’une administration optimisée du traitement par rapport aux systèmes conventionnels.
Conçu pour offrir une flexibilité maximale, une qualité d’image irréprochable et le plus grand format possible, ClearRT propose des fonctionnalités de pointe capables d’optimiser l’administration du traitement clinique.
Couvrant un mètre par minute, ce système assure le plus long balayage en continu de l’industrie (jusqu’à 135 cm), ce qui facilite et accélère la configuration des cibles étendues et permet de mieux adapter la planification en fonction des besoins. Avec son champ de vision de 50 cm, soit le plus vaste du secteur, ClearRT couvre d’importantes zones d’imagerie sans tronquer l’anatomie environnante, même chez les patients corpulents.
Grâce à la qualité de pointe et à la précision anatomique des clichés acquis par ClearRT, les cliniciens peuvent positionner rapidement les patients en vue du traitement, et ce, en toute confiance. En association avec le système de suivi de dose automatisé PreciseART®, les clichés ClearRT haute fidélité peuvent servir à déterminer s’il convient d’adapter le plan de traitement, puis à effectuer la replanification au moyen de PreciseRTX®.
ClearRT™ Helical kVCT Imaging for Radixact® Demo
*All demos in English unless specified
Meet with an Accuray representative to see and learn about the latest Helical kVCT Fan-beam Imaging for the Radixact® System.
Length: 30 – 45 min
Click Link to Register for Desired Day/Time
*Le système d’imagerie hélicoïdale kVCT ClearRT destiné au système d’administration de traitement Radixact® n’est pas commercialisé dans tous les pays. ClearRT peut faire l’objet de processus internationaux d’approbation réglementaire ou d’octroi de licence, d’où sa disponibilité variable selon les régions.
**Patient image & image data provided by Willis-Knighton Cancer Center, Shreveport (LA), USA
Avis de sécurité concernant la radiothérapie :
La plupart des effets secondaires de la radiothérapie, y compris lorsqu’elle est administrée à l’aide des systèmes Accuray, sont légers et transitoires. Les plus courants sont la fatigue, les nausées et les irritations cutanées. Certains effets secondaires graves peuvent toutefois survenir et causer des douleurs, une altération des fonctions normales de l’organisme (fonction urinaire ou salivaire, par exemple), une détérioration de la qualité de vie, des lésions permanentes, voire la mort. Les effets secondaires peuvent se manifester pendant ou peu de temps après la radiothérapie, ou dans les mois et années qui suivent. La nature et la gravité des effets secondaires dépendent de nombreux facteurs, notamment de la taille et de l’emplacement de la tumeur traitée, de la technique de traitement (dose de rayonnement, par exemple) ou encore de l’état de santé général du patient. Adressez-vous à votre médecin pour obtenir de plus amples informations sur les effets secondaires de votre radiothérapie et savoir si un produit Accuray est adapté dans votre cas.
