30 Years of Evidence

Take a moment to explore a selection of publications and conference abstracts from around the globe. Find evidence for a wide range of treatment sites including malignant and benign disease, different fractionation schedules and real-time motion synchronization techniques for the CyberKnife® and Radixact®/ TomoTherapy® platforms. We update new papers on a regular basis. See how health professionals are helping to improve patient outcomes.

Technical Note: Comprehensive performance tests of the first clinical real-time motion tracking and compensation system using MLC and jaws

Chen GP, Tai A, Keiper TD, Lim S, Li XA | Med Phys | 2020

Compensation of Intrafractional Motion for Lung Stereotactic Body Radiotherapy (SBRT) on Helical TomoTherapy

Price A, Chen J, Chao E, Schnarr E, Schreiber E, Lu L, Cox A, Chang S, Jian J. | Biomed. Phys. Eng. Express | 2019

Feasibility of Real-time Motion Management with Helical TomoTherapy

Schnarr E, Beneke M, Casey D, Chao E, Chappelow J, Cox A, Henderson D, Jordan P, Lessard E, Lucas D, Myronenko A, Mauer C | Med Phys | 2018

Evaluation of TomoTherapy Dose Calculations with Intrafractional Motion and Motion Compensation

Chao EH, Lucas D, Schnarr E | Med Phys | 2018

Characterization of imaging performance of a novel helical kVCT for use in image-guided and adaptive radiotherapy – PubMed (nih.gov)

Tegtmeier RC, Ferris WS, Bayouth JE, Miller JR, and Culberson WS | J Appl Clin Med Phys | 2022

Feasibility of image-guided robotic radiotherapy using three fractions for uveal melanoma

Choi SY, Kim MS, Yoo SY, Cho CK, Lhee CH, Lee DH, Kang JK, Shin YJ | Tumori | 2009

Stereotactic Radiosurgery and Fractionated Stereotactic Radiation Therapy for the Treatment of Uveal Melanoma

Yazici G, Kiratli H, Ozyigit G, Sari SY, Cengiz M, Tarlan B, Mocan BO, Zorlu F | Int J Radiat Oncol Biol Phys | 2017

Incidence of secondary glaucoma after treatment of uveal melanoma with robotic radiosurgery versus brachytherapy

Siedlecki J, Reiterer V, Leicht S, Foerster P, Kortüm K, Schaller U, Priglinger S, Fuerweger C, Muacevic A, Eibl-Lindner K | Acta Ophthalmol | 2017

Robotic assisted CyberKnife radiosurgery for the treatment of iris melanoma

Schmelter V, Heidorn S, Muacevic A, Priglinger SG, Foerster P, Liegl R | Melanoma Res | 2021

Robotic CyberKnife radiosurgery for small choroidal melanomas – PubMed (nih.gov)

Valerie Schmelter, Theresa Hofmann, Frederick Schneider, Constance Weber, Christoph Fuerweger, Alexander Muacevic, Siegfried G Priglinger, Paul Foerster, Raffael Liegl | Melanoma Res | 2022

Fiducial-free CyberKnife stereotactic body radiation therapy (SBRT) for single vertebral body metastases: acceptable local control and normal tissue tolerance with 5 fraction approach

Gill B, Oermann E, Ju A, Suy S, Yu X, Rabin J, Kalhorn C, Nair MN, Voyadzis JM, Unger K, Collins SP, Harter KW, Collins BT | Front Oncol | 2012

Stereotactic radiosurgery for metastasis to the craniovertebral junction preserves spine stability and offers symptomatic relief

Azad TD, Esparza R, Chaudhary N, Chang SD | Neurosurg Spine | 2016

Local failure and vertebral body fracture risk using multifraction stereotactic body radiation therapy for spine metastases

Mehta N, Zavitsanos PJ, Moldovan K, Oyelese A, Fridley JS, Gokaslan Z, Kinsella TJ, Hepel JT | Adv Radiat Oncol | 2018

Stereotactic Body Radiation Therapy With Simultaneous Integrated Boost in Patients With Spinal Metastases

Pontoriero A, Iatì G, Cacciola A, Conti A, Brogna A, Siragusa C, Ferini G, Davì V, Tamburella C, Molino L, Cambareri D, Severo C, Parisi S, Settineri N, Ielo I, Pergolizzi S | Technol Cancer Res Treat | 2020

Image-Guided Robotic Radiosurgery for the Management of Intramedullary Spinal Cord Metastases-A Multicenter Experience

Ehret F, Senger C, Kufeld M, Fürweger C, Kord M, Haidenberger A, Windisch P, Rueß D, Kaul D, Ruge M, Schichor C, Tonn JC, Muacevic A | Cancers (Basel) | 2021

Automated Deep Inspiration Breath-Hold (DIBH) in Breast Radiotherapy: A Comprehensive Assessment of the VitalHold System on the Radixact Platform

Retif P, Djibo Sidikou A, Gribelbauer J, Al Salah A, Pfletschinger E, Michel X | Phys Med | 2025

A Dosimetric Comparison of Helical TomoTherapy Treatment Delivery with Real-time Adaption and No Motion Correction

Hindmarsh J, Crowe S, Johnson J, Sengupta C, Walsh J, Dieterich S, Booth J, Keall P | Phys Imaging Radiat Oncol | 2025

Plan Quality Comparison at Five Years in Two Cohorts of Breast Cancer Patients Treated with Helical TomoTherapy

Dicuonzo S, Zerella MA, Zaffaroni M, Vincini MG, Amin K, Ronci G, D’arcangelo M, Rojas DP, Morra A, Gerardi MA, Fodor C, Cambria R, Luraschi R, Cattani F, Veronesi P, De Lorenzi F, Rietjens M, Orecchia R, Leonardi MC, Jereczek-Fossa BA | J Clin Med | 2025

Long-term Outcomes of Salvage Radiotherapy Using TomoTherapy With Image-guided Radiotherapy for Postoperative Prostate Cancer Patients

Mukai Y, Omura M, Minagawa Y, Mase M, Nishikawa Y, Miura I, Hata M | Cancer Diagn Progn | 2025

Long-Term Results of Intensity Modulated Radiotherapy (IMRT) with Helical Tomotherapy in Non-Metastatic Breast Cancer Patients: Final Analysis

Loap P, Uakkas A, Allali S, Bouziane J, Fourquet A, Kirova Y | Cancers (Basel) | 2025

Rationale, Implementation Considerations, Delineation and Planning Target Objective Recommendations for Volumetric Modulated Arc Therapy and Helical TomoTherapy Total Body Irradiation, Total Marrow Irradiation, Total Marrow and Lymphoid Irradiation and Total Lymphoid Irradiation

Hoeben BAW, Saldi S, Aristei C, Engellau J, Ocanto A, Hiniker SM, Misson-Yates S, Kobyzeva DA, Pazos M, George Mikhaeel N, Rodriguez-Roldan M, Seravalli E, Bosman ME, Han C, Losert C, Engström PE, Fulcheri CPL, Zucchetti C, Ferrer C, Hussein M, Loginova AA, Clark CH, Wong JYC | Radiother Oncol | 2025