30 Years of Evidence

Take a moment to explore a selection of publications and conference abstracts from around the globe. Find evidence for a wide range of treatment sites including malignant and benign disease, different fractionation schedules and real-time motion synchronization techniques for the CyberKnife® and Radixact®/ TomoTherapy® platforms. We update new papers on a regular basis. See how health professionals are helping to improve patient outcomes.

Revisiting Radioresistance: A Systematic Review of Outcomes of Stereotactic Radiosurgery (SRS) in Functional Head and Neck Paragangliomas

Verma O, Mantziaris G, Das L, Sheehan JP, Tripathi M | Neurosurg Rev. | 2025

Hypofractionated Radiosurgery (25 Gy/5 fractions) for Optic Nerve Sheath Meningiomas: Results from an Exploratory Phase 2 Prospective Trial

Fariselli L, Marzoli SB, Morlino S, Pinzi V, Pedone C, De Martin E, Romeo A, Tramacere I, Marchetti M | Int J Radiat Oncol Biol Phys. | 2025

Efficacy and Safety of Donut-Shaped Circumferential Spine CyberKnife Stereotactic Body Radiotherapy for Metastatic Spine Disease

Park DJ, Lee I, Annagiri S, Chou KN, Zamarud A, Akhavan-Sigari A, Hori YS, Persad AR, Abu-Reesh D, Lam FC, Tayag A, Ustrzynski L, Emrich SC, Gu X, Pollom EL, Chang SD | Neurosurgery. | 2025

Computed Tomography Guided Online Adaptive Stereotactic Body Radiation Therapy for Lymph Node Oligometastases: Impact on Dose to Target and Organs at Risk

van Werkhoven LA, Milder MTW, Schillemans W, Hoogeman MS, Nout RA, Nuyttens JJ | Int J Radiat Oncol Biol Phys. | 2025

Pattern of Recurrence After Fractionated Stereotactic Reirradiation in Adult Glioblastoma

Margulies A, Sahki N, Rech F, Vogin G, Blonski M, Peiffert D, Taillandier L, Lesanne G, Demogeot N | Radiat Oncol. | 2025

Low-Burden Oligometastatic Disease of the Lung Treated with Robotic Stereotactic Ablative Radiotherapy: A Retrospective Study

Zygogianni A, Koukourakis IM, Liakouli Z, Desse D, Georgakopoulos I, Armpilia C, Lymperopoulou G, Kouloulias V | Biomedicines. | 2025

Risk-adapted Stereotactic Body Radiation Therapy for the Treatment of Large (>3 cm) Primary Lung Cancer with or without Histologic Confirmation: A Propensity Score Matched and Weighted Analysis

Zeng HY, Li YJ, Ji CZ, Wang HH, Yu XR, He Y, Bai H, Zheng BY, Yan YY, Xu JW, Zaorsky NG, Shi JM, Dong Y, Yu XY, Wang JS, Song YC, Yuan ZY, Chen Y, Meng MB. | Radiother Oncol. | 2025

Local Control and Recurrence Patterns after Stereotactic Irradiation Delivered in more than 4 Fractions for Hepatocellular Carcinomas and liver metastases: a retrospective study

Renan A, Bruand M, Jolnerovski M, Diallo A, Demogeot N | Radiat Oncol. | 2025

Fractionated Robotic Radiosurgery for Unfavorable Nonfunctioning Pituitary Macroadenoma: 5-year Outcomes from a Single Institution Protocol

Bhatnagar A, Marin MP, Lischalk JW, Koh MJ, Agazzi S, Suy S, Harris BT, Sharma ST, Aulisi E, Anaizi A, Khattab MH, Jean WC, Collins SP, Collins BT | Front Oncol. | 2025

A Simple Plan Strategy to Optimize the Biological Effective Dose Delivered in Robotic Radiosurgery of Vestibular Schwannomas

Moutsatsos A, Pantelis E | Phys Med Biol. | 2025

Dosimetric Comparison of CyberKnife and Conventional Linac Prostate Stereotactic Body Radiation Therapy Plans: Analysis of the PACE-B Study

Ratnakumaran R, Sasitharan A, Khan A, Mayet H, Mohajer J, Hinder V, Brand DH, Fullarton R, Loblaw A, Hall E, van As N, Tree AC; PACE trial investigators | Int J Radiat Oncol Biol Phys. | 2025

Multicenter Approach to Predict Plan Quality of Robotic Intracranial SRS/SRT

Landoni V, Broggi S, Serra M, Doro R, Stefania Martinotti A, Redaelli I, Cristina Frassanito M, Siragusa C, De Martin E, Soriani A, Tudda A, Castriconi R, Del Vecchio A, Masi L, Fiorino C | Phys Med. | 2025

Late Radiation-related Lymphopenia After Prostate Stereotactic Body Radiation Therapy Plus or Minus Supplemental Pelvic Irradiation

Gaudian K, Koh MJ, Koh MJ, Jermain P, Khan I, Kallam D, Lee Z, Collins RR, Zwart Z, Danner M, Zwart A, Kumar D, Atkins MB, Suy S, Collins SP | Front Oncol. | 2024

Results of a Single Arm Phase II Clinical Trial: Online-Adaptive Stereotactic Body Radiotherapy of Abdominal-Pelvic Oligometastases

van Werkhoven LA, Milder MTW, Hoogeman MS, van Werkhoven E, Nout RA, Nuyttens JJ | Int J Radiat Oncol Biol Phys. | 2025

Fractionated Stereotactic Radiotherapy of Brainstem Metastases – Clinical Outcome and Prognostic Factors

Krämer A, Hahnemann L, Schunn F, Grott CA, Thomas M, Christopoulos P, Lischalk JW, Hörner-Rieber J, Hoegen-Saßmannshausen P, Eichkorn T, Deng MY, Meixner E, Lang K, Paul A, Weykamp F, Debus J, König L | Clin Transl Radiat Oncol. | 2025