Featured Abstracts
Review key findings and research highlights presented at major industry conferences and events.
Featured Content
ESTRO 2026
Preoperative radiotherapy in a single fraction for early stage breast cancer: the CRYSTAL phase I/II study update (AIRC IG-23118)
ESTRO 2026
Initial clinical experience of RayStation-based online adaptive RT using Radixact for endometrial cancer.
ESTRO 2026
One-year cumulative toxicity in 25 prostate cancer patients treated with single fraction (24 Gy) urethra-sparing radiosurgery (PRO-FAST NCT05936736 )
Featured Case Studies

Robotic Stereotactic Body Radiation Therapy For High-risk Prostate Cancer: The Georgetown University Experience
This retrospective study examines cancer control and health-related quality of life (HRQOL) outcomes in high-risk prostate cancer patients receiving robotic stereotactic body radiation therapy (SBRT) with Synchrony® real-time adaptive motion management.

Use of Motion Management to Model Unmanaged Motion: Dosimetric Consequences of Unmanaged Prostate Motion Assessed Using Real-time Radiotherapy Adaptation Data
This case report explores the dosimetric impact of unmanaged intrafraction prostate motion during radiotherapy by retrospectively analyzing real-time motion data collected using the Radixact® System with Synchrony®. The study models what would have happened if a patient had been treated without motion management, using deformation vector fields to simulate dose

Stereotactic Body Radiotherapy of a Lung Tumor with Large Respiratory Motion Using Real-time Adaptive Motion Management: A Case Report
Traditional internal target volume (ITV) methods for the treatment of a lung tumor on conventional linac would require a large planning target volume (PTV), risking high radiation exposure to the chest wall and lungs.
4009: Film Dosimetry for Surface Irradiation Without Physical Bolus, Calculated in RayStation for Radixact X9
Edwin Rozo et al. | ESTRO | 2025
3802: Clinical Evaluation of Quality Assurance Method Using 4D Moving Phantom for Synchrony’s Lung Tumor Tracking
Koji Sasaki et al. | ESTRO | 2025
4034: Initial Experience and Short-Term Clinical Outcomes of Lung cancer Patients Treated with SBRT Using the Radixact Synchrony Tumor Tracking System
Kadriye Tezcanli et al. | ESTRO | 2025
3734: Analysis and Comparison of CyberKnife MLC Collimator Versus IRIS Collimator in Prostate SBRT
Gaetano Gagliardo et al. | ESTRO | 2025
2226: Impact of Using a Virtual Reality Headset Before Stereotactic Radiotherapy Sessions with CyberKnife®
Ilan Darmon et al. | ESTRO | 2025
3355: Development and Validation of a Knowledge-Based Model for Automated CyberKnife Planning in Brain Lesions
Rita C. Buono et al. | ESTRO | 2025
2302: Correlation of Lung Tumor Motion with Clinical Covariates: A Retrospective Evaluation of CyberKnife Synchrony Data
Ashlesha Gill et al. | ESTRO | 2025
3492: CyberKnife UH-SBRT for Localized Prostate Cancer and DIL: Preliminary Report of Acute and Late Toxicity of the PRO-SPEED Trial (NCT06331013)
Giovanni Carlo Mazzola et al. | ESTRO | 2025
3039: A Single Institution Study of Efficacy and Toxicity Outcomes of Spinal SBRT in Prostate Cancer
Binnaz Yasar et al. | ESTRO | 2025
1653: Early Results from a Trial on Stereotactic Salvage Radiotherapy for Macroscopic Prostate Bed Recurrence After Prostatectomy: STARR (NCT05455736)
Niccolo’ Bertini et al. | ESTRO | 2025