20+ Years of Evidence

Join the experts’ corner

This page presents publications and webinars from around the globe. It includes evidence for a wide range of treatment sites including malignant and benign disease, different fractionation schedules and motion synchronization techniques for both the CyberKnife® and TomoTherapy® platforms. We update new papers on a regular basis. Please take a moment to explore the page and see the evidence we have collected to truly demonstrate how we are making a change to peoples’ lives.

ASTRO

Oral Presentation

Patterns and Outcomes of Relapse Treated With Radiotherapy Following Total Marrow and Lymphoid Irradiation in High-Risk and/or Relapsed/Refractory Acute Leukemia Annual Meeting 2021 (core-apps.com) on Wednesday, October 27, 2021 11:05 AM (CDT)

Posters

Robotic SBRT in Prostate Cancer Patients Younger Than 50 Years Old Annual Meeting 2021 (core-apps.com)
The use of Robotic SBRT for the treatment of localized prostate cancer in men with ultra-large prostate gland is feasible with minimal toxicity and excellent oncologic outcomes observed. Annual Meeting 2021 (core-apps.com)
Early Follow-up of Multi-Institutional Trial of Phase I Dose Escalation Using Single Fraction Stereotactic Partial Breast Irradiation (S-PBI) for Early Stage Breast Cancer Annual Meeting 2021 (core-apps.com)
A Prospective, Single-Arm, Phase II, Multi-Center Study of Stereotactic Body Radiation Therapy for Low- and Intermediate-Risk Prostate Cancer Annual Meeting 2021 (core-apps.com)
Efficacy of Frameless Radiosurgical Entorhino-Amygdalohippocampectomy for Pharmacoresistant Medial Temporal Lobe Epilepsy Annual Meeting 2021 (core-apps.com)
Frameless Multisession Radiosurgery for Symptomatic Circumscribed Choroidal Hemangioma Annual Meeting 2021 (core-apps.com)
Multivariate Model for Predicting Overall Survival in Malignant Pleural Mesothelioma After Adjuvant Radiotherapy Annual Meeting 2021 (core-apps.com)
Evaluation of Two Intensity Modulated Radiotherapy Techniques for Total Body Irradiation: Initial Clinical Experience From an Ongoing Pilot Study Annual Meeting 2021 (core-apps.com)
Stereotactic Body Radiotherapy (SBRT) for Multiple Synchronous Oligometastases (<5) Lung Lesions: Early Clinical Outcomes Annual Meeting 2021 (core-apps.com)
Real-Time Motion Tracking and Correction During Tomotherapy for Prostate Cancer: Impact of Fiducial Migration Annual Meeting 2021 (core-apps.com)
Comparison of the Kinetics of Hematologic Recovery in Aplastic Anemia After Total Nodal Irradiation Between Helical Tomotherapy and Conventional Radiotherapy Annual Meeting 2021 (core-apps.com)

Ultra-Hypofractionated Radiotherapy

CyberKnife Liver

Publications

Sun J, Wang Q, Hong ZX, Li WG, He WP, Zhang T, Zhang AM, Fan YZ, Sun YZ, Zheng L, Duan XZ. Stereotactic body radiotherapy versus hepatic resection for hepatocellular carcinoma (≤ 5 cm): a propensity score analysis. Hepatol Int. 2020 Sep 4.

CyberKnife Pancreas

Publications

Ji X, Zhao Y, He C, Han S, Zhu X, Shen Z, Chen C, Chu X. Clinical Effects of Stereotactic Body Radiation Therapy Targeting the Primary Tumor of Liver-Only Oligometastatic Pancreatic Cancer. Front Oncol. 2021 May 27;11:659987.
Jumeau R, Delouya G, Roberge D, Donath D, Béliveau-Nadeau D, Campeau MP. Stereotactic body radiotherapy (SBRT) for patients with locally advanced pancreatic cancer: A single center experience. Dig Liver Dis. 2018 Apr;50(4):396-400.
Zhu X, Li F, Ju X, Cao F, Cao Y, Fang F, Qing S, Shen Y, Jia Z, Zhang H. Prognostic role of stereotactic body radiation therapy for elderly patients with advanced and medically inoperable pancreatic cancer. Cancer Med. 2017 Oct;6(10):2263-2270.
Zeng XL, Wang HH, Meng MB, Wu ZQ, Song YC, Zhuang HQ, Qian D, Li FT, Zhao LJ, Yuan ZY, Wang P. Stereotactic body radiation therapy for patients with recurrent pancreatic adenocarcinoma at the abdominal lymph nodes or postoperative stump including pancreatic stump and other stump. Onco Targets Ther. 2016 Jun 30;9:3985-92.

TomoTherapy Lung

Publications

Figlia V, Mazzola R, Cuccia F, Alongi F, Mortellaro G, Cespuglio D, Cucchiara T, Iacoviello G, Valenti V, Molino M, Verderame F, Matranga D, Casto AL, Ferrera G. Hypo-fractionated stereotactic radiation therapy for lung malignancies by means of helical tomotherapy: report of feasibility by a single-center experience. Radiol Med. 2018 Jun;123(6):406-414.

TomoTherapy Liver

Publications

Shen J, Yan J, Zhu S, Kong W, Zou Z, Liu J, Li S, Liu B. The Efficacy and Safety of Hypofractionated Radiation Therapy With Tomotherapy for Advanced or Recurrent Hepatocellular Carcinoma. Front Oncol. 2021 May 31;11:559112
Kim JY, Yoo EJ, Jang JW, Kwon JH, Kim KJ, Kay CS. Hypofractionated radiotheapy using helical tomotherapy for advanced hepatocellular carcinoma with portal vein tumor thrombosis. Radiat Oncol. 2013 Jan 16;8:15.

TomoTherapy Prostate

Publications

Macias VA, Barrera-Mellado I. Ultra-hypofractionated radiation therapy for unfavourable intermediate-risk and high-risk prostate cancer is safe and effective: 5-year outcomes of a phase II trial. BJU Int. 2020 Feb;125(2):215-225.

IG-IMRT Treatment

TomoTherapy Intracranial

Publications

Arpa D, Parisi E, Ghigi G, Savini A, Colangione SP, Tontini L, Pieri M, Foca F, Polico R, Tesei A, Sarnelli A, Romeo A. Re-irradiation of recurrent glioblastoma using helical TomoTherapy with simultaneous integrated boost: preliminary considerations of treatment efficacy. Sci Rep. 2020 Nov 9;10(1):19321
Boulle G, Bracci S, Hitchcock K, Jacob J, Clausse E, Halley A, Belghith B, Kamsu Kom L, Canova CH, Bielle F, Chevalier A, Peyre M, Mazeron JJ, Maingon P, Feuvret L. Treatment of grade II-III intracranial meningioma with helical tomotherapy. J Clin Neurosci. 2019 Jan;59:190-196.

TomoTherapy Head & Neck

Publications

Fan WJ, Teng F, Liu G, Zhao DW, Li JF, Luo YR, Zhang XX, Ma L, Guan J. Diffusion weighted imaging in submandibular gland sparing helical tomotherapy for nasopharyngeal carcinoma. Radiother Oncol. 2021 Feb 12:S0167-8140(21)06050-3
Chen N, Yuan H, Fan W, Ma L, Liu K, Chen L, Yang S, Zhang X. Multimodal Treatment With Orbital Organ Preservation in Adult Patients With Locally Advanced Small-Round-Cell Malignancy of the Nasal Cavity and Paranasal Sinus. Front Oncol. 2021 Apr 1;11:650385
T Liu Z, Xu C, Jiang R, Liu G, Liu Q, Zhou J, Liu F, Yao J, Wang S, Jiang W. Treatment of Locally Advanced Nasopharyngeal Carcinoma by Helical Tomotherapy: An Observational, Prospective Analysis. Transl Oncol. 2019 May;12(5):757-763.
Moroney LB, Helios J, Ward EC, Crombie J, Pelecanos A, Burns CL, Spurgin AL, Blake C, Kenny L, Chua B, Hughes BGM. Helical intensity-modulated radiotherapy with concurrent chemotherapy for oropharyngeal squamous cell carcinoma: A prospective investigation of acute swallowing and toxicity patterns. Head Neck. 2018 Sep;40(9):1955-1966.
Bibault JE, Dussart S, Pommier P, Morelle M, Huguet M, Boisselier P, Coche-Dequeant B, Alfonsi M, Bardet E, Rives M, Calugaru V, Chajon E, Noel G, Mecellem H, Servagi Vernat S, Perrier L, Giraud P. Clinical Outcomes of Several IMRT Techniques for Patients With Head and Neck Cancer: A Propensity Score-Weighted Analysis. Int J Radiat Oncol Biol Phys. 2017 Nov 15;99(4):929-937.
Du L, Zhang XX, Feng LC, Qu BL, Chen J, Yang J, Liu HX, Xu SP, Xie CB, Ma L. Propensity score matching analysis of a phase II study on simultaneous modulated accelerated radiation therapy using helical tomotherapy for nasopharyngeal carcinomas. BMC Cancer. 2017 Aug 29;17(1):582.
Chitapanarux I, Nobnop W, Sripan P, Chumachote A, Tharavichitkul E, Chakrabandhu S, Klunklin P, Onchan W, Jia-Mahasap B, Janlaor S, Kayan P, Traisathit P, Van Gestel D. The Outcome of the First 100 Nasopharyngeal Cancer Patients in Thailand Treated by Helical Tomotherapy. Radiol Oncol. 2017 Apr 21;51(3):351-356.
Du L, Zhang XX, Feng LC, Chen J, Yang J, Liu HX, Xu SP, Xie CB, Ma L. Treatment of nasopharyngeal carcinoma using simultaneous modulated accelerated radiation therapy via helical tomotherapy: a phase II study. Radiol Oncol. 2016 Feb 7;50(2):218-25.
Kimura K, Kodaira T, Tomita N, Tachibana H, Makita C, Yoshida M, Nishikawa D, Hirakawa H, Suzuki H, Hanai N, Hasegawa Y. Clinical results of definitive intensity-modulated radiation therapy for oropharyngeal cancer: retrospective analysis of treatment efficacy and safety. Jpn J Clin Oncol. 2016 Jan;46(1):78-85.

Videos

The Outcome of the First 100 Nasopharyngeal Cancer Patients in Thailand Treated by Helical TomoTherapy®. Imjai Chitapanarux M.D., Chiang Mai University, Chiang Mai, Thailand.
Clinical Outcomes of Several IMRT Techniques for Patients With Head and Neck Cancer: A Propensity Score-Weighted Analysis. Jean-Emmanuel Bibault, M.D., MSc, Georges-Pompidou European Hospital, Paris, France.
Impact of Postoperative Daily Image-Guided Intensity-Modulated Radiotherapy on Overall and Local Progression-Free Survival in Patients with Oral Cavity Cancer. Pei-Wei Shueng, MD, Far Eastern Memorial Hospital, New Taipei, Taiwan.

TomoTherapy Breast

Publications

Leonardi MC, Kouloura A, Rojas DP, Zaffaroni M, Intra M, Veronesi P, Morra A, Gerardi MA, Fodor CI, Zerella MA, Camarda AM, Cattani F, Luraschi R, Viola A, Riva G, Miglietta E, Orecchia R, Dicuonzo S, Jereczek-Fossa BA. The POLO (Partially Omitted Lobe) approach to safely treat in-breast recurrence after intraoperative radiotherapy with electrons. Br J Radiol. 2021 Dec 17:20210405.
Van Parijs H, Vinh-Hung V, Fontaine C, Storme G, Verschraegen C, Nguyen DM, Adriaenssens N, Nguyen NP, Gorobets O, De Ridder M. Cardiopulmonary-related patient-reported outcomes in a randomized clinical trial of radiation therapy for breast cancer. BMC Cancer. 2021 Nov 4;21(1):1177.
de Paula U, D’Angelillo RM, Andrulli AD, Apicella G, Caruso C, Ghini C, Gomellini S, Ponti E, Pompei M, Caccavari A, Petrocchi A, Costarelli L, Giordano M, La Pinta M, Meli EZ, Mauri M, Minelli M, Rossi R, Scavina P, Broglia L, Ponzani T, Loreti A, Fortunato L. Long-Term Outcomes of Once-Daily Accelerated Partial-Breast Irradiation With Tomotherapy: Results of a Phase 2 Trial. Int J Radiat Oncol Biol Phys. 2021 Mar 1;109(3):678-687.
Bataille B, Raoudha B, Le Tinier F, Basson L, Escande A, Langin H, Tresch E, Crop F, Darloy F, Carlier D, Lartigau E, Pasquier D. Prospective Study of Intensity-Modulated Radiation Therapy for Locally Advanced Breast Cancer. Cancers (Basel). 2020 Dec 20;12(12)
Joseph K, Vos LJ, Gabos Z, Pervez N, Chafe S, Tankel K, Warkentin H, Ghosh S, Amanie J, Powell K, Polkosnik LA, Horsman S, MacKenzie M, Sabri S, Parliament MB, Mackey J, Abdulkarim B. Skin Toxicity in Early Breast Cancer Patients Treated with Field-In-Field Breast Intensity-Modulated Radiotherapy versus Helical Inverse Breast Intensity-Modulated Radiotherapy: Results of a Phase III Randomised Controlled Trial. Clin Oncol (R Coll Radiol). 2020 Jul 22:S0936-6555(20)30287-9.
Mathieu D, Bedwani S, Mascolo-Fortin J, Côté N, Bernard AA, Roberge D, Yassa M, Bahig H, Vu T. Cardiac Sparing with Personalized Treatment Planning for Early-stage Left Breast Cancer. Cureus. 2020 Mar 12;12(3):e7247.
Chitapanarux I, Nobnop W, Tippanya D, Sripan P, Chakrabandhu S, Klunklin P, Onchan W, Jia-Mahasap B, Tharavichitkul E. Clinical outcomes and dosimetric study of hypofractionated Helical TomoTherapy in breast cancer patients. PLoS One. 2019 Jan 31;14(1):e0211578.
Arsene-Henry A, Foy JP, Robilliard M, Xu HP, Bazire L, Peurien D, Poortmans P, Fourquet A, Kirova YM. The use of helical tomotherapy in the treatment of early stage breast cancer: indications, tolerance, efficacy-a single center experience. Oncotarget. 2018 May 4;9(34):23608-23619.
Thery L, Arsene-Henry A, Carroll S, Peurien D, Bazire L, Robilliard M, Fourquet A, Kirova YM. Use of helical tomotherapy in locally advanced and/or metastatic breast cancer for locoregional treatment. Br J Radiol. 2018 May;91(1085):20170822.
Orecchia R, Rojas DP, Cattani F, Ricotti R, Santoro L, Morra A, Cambria R, Luraschi R, Dicuonzo S, Ronchi S, Surgo A, Dell’ Acqua V, Veronesi P, De Lorenzi F, Fodor C, Leonardi MC, Jereczek-Fossa BA. Hypofractionated postmastectomy radiotherapy with helical tomotherapy in patients with immediate breast reconstruction: dosimetric results and acute/intermediate toxicity evaluation. Med Oncol. 2018 Feb 13;35(3):39.

Videos

Clinical Outcomes and Dosimetric Study of Hypofractionated Helical TomoTherapy® in Breast Cancer Patients. Imjai Chitapanarux M.D., Chiang Mai University, Chiang Mai, Thailand.
A Comprehensive Radiotherapy Strategy for Managing Breast Cancer. Rupesh Kotecha, M.D., Miami Cancer Institute, Miami, FL, USA.
Breast Cancer: Your Challenges Today – Our Solutions for Tomorrow. Nathan Corradini, MS, DABR, SSRMP, Clinica Luganese, Lugano, Switzerland, Carole Massabeau, M.D., Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France, and Jennifer R. Bellon, M.D. Dana-Farber Cancer Institute, Boston, MA, USA.
Benefits of TomoDirect™ to Treat Breast Cancer. Nathan Corradini, M.S., DABR, SSRMP, Clinica Luganese, Lugano, Switzerland.
Using the Tomotherapy® System for Whole Breast Irradiation in the Community Clinic Setting. Robert A. Harris, M.D., Gamma West, Layton, UT, USA.

TomoTherapy Lung

Publications

Vekens K, Verbanck S, Collen C, Storme G, Barbé K, De Ridder M, Vanderhelst E. Pulmonary function changes following helical tomotherapy in patients with inoperable, locally advanced non-small cell lung cancer. Strahlenther Onkol. 2020 Feb;196(2):142-150.

TomoTherapy Mesothelioma

Publications

Hong JH, Lee HC, Choi KH, Moon SW, Kim KS, Hong SH, Hong JY, Kim YS. Preliminary results of entire pleural intensity-modulated radiotherapy in a neoadjuvant setting for resectable malignant mesothelioma. Radiat Oncol J. 2019 Jun;37(2):101-109.
Harrabi SB, Koerber SA, Adeberg S, Katayama S, Herfarth K, Debus J, Sterzing F. Malignant pleural mesothelioma – Pleural cavity irradiation after decortication with helical tomotherapy. Rep Pract Oncol Radiother. 2017 Sep-Oct;22(5):402-407.
Kishan AU, Cameron RB, Wang PC, Alexander S, Qi SX, Low DA, Kupelian PA, Steinberg ML, Lee JM, Selch MT, Lee P. Tomotherapy improves local control and changes failure patterns in locally advanced malignant pleural mesothelioma. Pract Radiat Oncol. 2015 Nov-Dec;5(6):366-73.

TomoTherapy Liver

Publications

Okada W, Doi H, Tanooka M, Sano K, Nakamura K, Sakai Y, Shibata M, Tanaka M. A first report of tumour-tracking radiotherapy with helical tomotherapy for lung and liver tumours: A double case report. SAGE Open Med Case Rep. 2021 Jun 12;9:2050313X211023688.
Chen YX, Zhuang Y, Yang P, Fan J, Zhou J, Hu Y, Zhu WC, Sun J, Zeng ZC. Helical IMRT-Based Stereotactic Body Radiation Therapy Using an Abdominal Compression Technique and Modified Fractionation Regimen for Small Hepatocellular Carcinoma. Technol Cancer Res Treat. 2020 Jan-Dec;19:1533033820937002
Jung J, Kong M, Hong SE. Conventional fractionated helical tomotherapy for patients with small to medium hepatocellular carcinomas without portal vein tumor thrombosis. Onco Targets Ther. 2014 Sep 26;7:1769-75.
Yoon HI, Lee IJ, Han KH, Seong J. Improved oncologic outcomes with image-guided intensity-modulated radiation therapy using helical tomotherapy in locally advanced hepatocellular carcinoma. J Cancer Res Clin Oncol. 2014 Sep;140(9):1595-605.

TomoTherapy Bladder

Publications

Murthy V, Gupta P, Baruah K, Krishnatry R, Joshi A, Prabhash K, Noronha V, Menon S, Pal M, Prakash G, Bakshi G. Adaptive Radiotherapy for Carcinoma of the Urinary Bladder: Long-term Outcomes With Dose Escalation Clin Oncol (R Coll Radiol). 2019 Sep;31(9):646-652.

TomoTherapy Prostate

Publications

Ferrera G, D’Alessandro S, Cuccia F, Serretta V, Trapani G, Savoca G, Mortellaro G, Lo Casto A. Post-operative hypofractionated radiotherapy for prostate cancer: a mono-institutional analysis of toxicity and clinical outcomes. J Cancer Res Clin Oncol. 2022 Jan;148(1):89-95.
Onishi M, Kawamura H, Murata K, Inoue T, Murata H, Takakusagi Y, Okonogi N, Ohkubo Y, Okamoto M, Kaminuma T, Sekihara T, Nakano T, Ohno T. Intensity-Modulated Radiation Therapy with Simultaneous Integrated Boost for Clinically Node-Positive Prostate Cancer: A Single-Institutional Retrospective Study. Cancers (Basel). 2021 Jul 31;13(15):3868.
Yamazaki H, Masui K, Suzuki G, Nakamura S, Shimizu D, Nishikawa T, Okabe H, Yoshida K, Kotsuma T, Tanaka E, Otani K, Yoshioka Y, Ogawa K. High-Dose-Rate Brachytherapy Monotherapy versus Image-Guided Intensity-Modulated Radiotherapy with Helical Tomotherapy for Patients with Localized Prostate Cancer. Cancers (Basel). 2018 Sep 10;10(9):322.
Di Muzio NG, Fodor A, Noris Chiorda B, Broggi S, Mangili P, Valdagni R, Dell’Oca I, Pasetti M, Deantoni CL, Chiara A, Berardi G, Briganti A, Calandrino R, Cozzarini C, Fiorino C. Moderate Hypofractionation with Simultaneous Integrated Boost in Prostate Cancer: Long-term Results of a Phase I-II Study. Clin Oncol (R Coll Radiol). 2016 Aug;28(8):490-500.
Tomita N, Soga N, Ogura Y, Hayashi N, Kageyama T, Ito M, Koide Y, Yoshida M, Kimura K, Makita C, Tachibana H, Kodaira T. High-dose radiotherapy with helical tomotherapy and long-term androgen deprivation therapy for prostate cancer: 5-year outcomes. J Cancer Res Clin Oncol. 2016 Jul;142(7):1609-19.

Videos

Safe and Effective Stereotactic Body Radiation Therapy (SBRT) for High-Risk Prostate Cancer Patients: 4-year Outcomes of a Phase II Trial. Victor Macias Hernandez, M.D., Ph.D., Salamanca University Hospital, Valladolid University Hospital, Spain.

TomoTherapy Gynecological

Publications

Ye X, Ye P, Zheng Y, Xia W. Efficacy of helical tomotherapy combined with CT-guided three-dimensional intracavitary brachytherapy in treatment of locally advanced cervical cancer. J BUON. 2021 Jul-Aug;26(4):1298-1305.
Zhang G, He F, Miao L, Wu H, Zhang Y, Fu C. Post-operative small pelvic intensity-modulated radiation therapy for early-stage cervical cancer with intermediate-risk factors: efficacy and toxicity. Jpn J Clin Oncol. 2021 May 28;51(6):905-910.
Mukai Y, Minagawa Y, Inoue H, Sato A, Matsui K, Fukuda T, Onuma K, Hongo H, Shirata R, Nagata H, Hashimoto H, Inoue T, Hata M, Omura M. Treatment Outcome of the Combination Therapy of High-dose rate Intracavitary Brachytherapy and Intensity-modulated Radiation Therapy With Central-shielding for Cervical Cancer. In Vivo. 2020 Nov-Dec;34(6):3387-3398
Kim S, Lee S, Hong JH, Park YJ, Song JY, Lee JK, Lee NW. Comparing efficacy of high-dose rate brachytherapy versus helical tomotherapy in the treatment of cervical cancer. J Gynecol Oncol. 2020 Jul;31(4):e42.
Arians N, Kieser M, Benner L, Rochet N, Schröder L, Katayama S, Herfarth K, Schubert K, Schneeweiss A, Sohn C, Lindel K, Debus J. Adjuvant intensity modulated whole-abdominal radiation therapy for high-risk patients with ovarian cancer FIGO stage III: final results of a prospective phase 2 study. Radiat Oncol. 2019 Oct 21;14(1):179.
Cordoba A, Nickers P, Tresch E, Castelain B, Leblanc E, Narducci F, Le Tinier F, Lesoin A, Lacornerie T, Lartigau E. Safety of adjuvant intensity-modulated postoperative radiation therapy in endometrial cancer: Clinical data and dosimetric parameters according to the International Commission on Radiation Units (ICRU) 83 report. Rep Pract Oncol Radiother. 2015 Sep-Oct;20(5):385-92.
Chitapanarux I, Tharavichitkul E, Nobnop W, Wanwilairat S, Vongtama R, Traisathit P. A comparative planning study of step-and-shoot IMRT versus helical tomotherapy for whole-pelvis irradiation in cervical cancer. J Radiat Res. 2015 May;56(3):539-45.

TomoTherapy Rectal Cancer

Publications

Karaca S, Aysenur Arli Karacam K. A comparison of dosimetric and clinical parameters between different IMRT boost techniques in preoperative rectal cancer. J BUON. 2021 Jul-Aug;26(4):1231-1238.
De Bari B, Franzetti-Pellanda A, Saidi A, Biggiogero M, Hahnloser D, Montemurro M, Bourhis J, Zeverino M, Ozsahin M. Neoadjuvant chemoradiotherapy delivered with helical tomotherapy under daily image guidance for rectal cancer patients: efficacy and safety in a large, multi-institutional series. J Cancer Res Clin Oncol. 2019 Apr;145(4):1075-1084.
Zhao J, Liu X, Wang W, Hu K, Zhang F, Hou X, Meng Q. Concomitant dose escalation with image-guided Tomotherapy in locally advanced mid-low rectal cancer: a single-center study. Cancer Manag Res. 2019 Feb 15;11:1579-1586.
Huang CM, Huang MY, Tsai HL, Huang CW, Ma CJ, Lin CH, Huang CJ, Wang JY. A retrospective comparison of outcome and toxicity of preoperative image-guided intensity-modulated radiotherapy versus conventional pelvic radiotherapy for locally advanced rectal carcinoma. J Radiat Res. 2017 Mar 1;58(2):247-259.

Videos

Role of the TomoTherapy® System in the Treatment of Rectal Cancer. Berardino De Bari M.D., University Hospital of Besançon, Besançon, France.
TomoTherapy® for Advanced Rectal Cancer. Xiaoliang Liu, M.D., Peking Union Medical College Hospital, Beijing, China.

TomoTherapy Anal Cancer

Publications

Klausner G, Blais E, Jumeau R, Biau J, de Meric de Bellefon M, Ozsahin M, Zilli T, Miralbell R, Thariat J, Troussier I. Management of locally advanced anal canal carcinoma with intensity-modulated radiotherapy and concurrent chemotherapy. Med Oncol. 2018 Aug 20;35(10):134.
De Bari B, Lestrade L, Franzetti-Pellanda A, Jumeau R, Biggiogero M, Kountouri M, Matzinger O, Miralbell R, Bourhis J, Ozsahin M, Zilli T. Modern intensity-modulated radiotherapy with image guidance allows low toxicity rates and good local control in chemoradiotherapy for anal cancer patients. J Cancer Res Clin Oncol. 2018 Apr;144(4):781-789.
Joseph K, Vos LJ, Warkentin H, Paulson K, Polkosnik LA, Usmani N, Tankel K, Severin D, Nijjar T, Schiller D, Wong C, Ghosh S, Mulder K, Field C. Patient reported quality of life after helical IMRT based concurrent chemoradiation of locally advanced anal cancer. Radiother Oncol. 2016 Aug;120(2):228-33.
Koerber SA, Slynko A, Haefner MF, Krug D, Schoneweg C, Kessel K, Kopp-Schneider A, Herfarth K, Debus J, Sterzing F. Efficacy and toxicity of chemoradiation in patients with anal cancer–a retrospective analysis. Radiat Oncol. 2014 May 13;9:113.

TomoTherapy Sarcoma

Publications

Salfelder MA, Kessel KA, Thiel U, Burdach S, Kampfer S, Combs SE. Prospective evaluation of multitarget treatment of pediatric patients with helical intensity-modulated radiotherapy. Strahlenther Onkol. 2020 Aug 3.
Peeken JC, Knie C, Kessel KA, Habermehl D, Kampfer S, Dapper H, Devecka M, von Eisenhart-Rothe R, Specht K, Weichert W, Wörtler K, Knebel C, Wilkens JJ, Combs SE. Neoadjuvant image-guided helical intensity modulated radiotherapy of extremity sarcomas – a single center experience. Radiat Oncol. 2019 Jan 9;14(1):2.
Yu JI, Lim DH, Park HC, Jung SH, Jeon SJ, Nam H, Kim B, Kim SJ, Park JB. Effectiveness and Safety of Tissue Expander for Adjuvant Helical Tomotherapy in Curatively Resected Retroperitoneal Sarcoma. Anticancer Res. 2018 Apr;38(4):2447-2453.

TomoTherapy Superficial

Publications

Haraldsson A, Engleson J, Bäck SÅJ, Engelholm S, Engström PE. A Helical tomotherapy as a robust low-dose treatment alternative for total skin irradiation. J Appl Clin Med Phys. 2019 May;20(5):44-54.
Hsieh CH, Tien HJ, Yu YB, Wu YH, Shueng PW, Lu YF, Wang SY, Wang LY. Simultaneous integrated boost with helical arc radiotherapy of total skin (HEARTS) to treat cutaneous manifestations of advanced, therapy-refractory cutaneous lymphoma and leukemia – dosimetry comparison of different regimens and clinical application. Radiat Oncol. 2019 Jan 28;14(1):17.
Dar AR, Jordan K, Yartsev S. Secondary Cutaneous Involvement in Follicular Diffuse Lymphoma Treated with Helical Tomotherapy. Cureus. 2017 Jul 14;9(7):e1471.
Cuccia F, Figlia V, Palmeri A, Verderame F, Lo Casto A, Mannino M, Ferrera G. Helical Tomotherapy_®is a Safe and Feasible Technique for Total Scalp Irradiation. Rare Tumors. 2017 Mar 28;9(1):6942.
Elsayad K, Kriz J, Haverkamp U, Plachouri KM, Jeskowiak A, Sunderkötter C, Eich HT. Treatment of folliculitis decalvans using intensity-modulated radiation via tomotherapy. Strahlenther Onkol. 2015 Nov;191(11):883-8.
Falivene S, Giugliano FM, Grimaldi AM, Di Franco R, Toledo D, Muto M, Cammarota F, Borzillo V, Ascierto PA, Muto P. Tomotherapy concomitant with cetuximab, followed by cetuximab as single-agent therapy for unresectable squamous cell carcinoma of the skin: a case report. BMC Dermatol. 2014 Sep 30;14:15.
Katayama S, Hantschke M, Lissner S, Lindel K, Oetzel D, Herfarth K, Debus J, Sterzing F. Helical tomotherapy of the complete scalp and the ipsilateral lymph nodes in a case of scalp angiosarcoma. Ear Nose Throat J. 2014 Jun;93(6):E24-8.
Chatterjee S, Mott JH, Dickson S, Kelly CG. Extensive basal cell carcinoma of the forehead and anterior scalp: use of helical tomotherapy as a radiotherapy treatment modality. Br J Radiol. 2010 Jun;83(990):538-40. doi: 10.1259/bjr/64114980.

Long Fields Treatment

TomoTherapy Total Body Irradiation

Publications

Rassiah P, Esiashvili N, Olch AJ, Hua CH, Ulin K, Molineu A, Marcus K, Gopalakrishnan M, Pillai S, Kovalchuk N, Liu A, Niyazov G, Peñagarícano J, Cheung F, Olson AC, Wu CC, Malhotra HK, MacEwan IJ, Faught J, Breneman JC, Followill DS, FitzGerald TJ, Kalapurakal JA. Practice Patterns of Pediatric Total Body Irradiation Techniques: A Children’s Oncology Group Survey. Int J Radiat Oncol Biol Phys. 2021 Dec 1;111(5):1155-1164.
Sresty NVNM, Gudipudi D, Krishnam Raju A, Anil Kumar T, Lakshmi VRP, Srikanth G, Narasimha M. Total body irradiation of bone marrow transplant using helical TomoTherapy with a focus on the quality of dose contribution at junction target volumes. Strahlenther Onkol. 2021 Aug;197(8):722-729.
Wilhelm-Buchstab T, Leitzen C, Schmeel LC, Simon B, Koch D, Schmeel FC, Schoroth F, Garbe S, Röhner F, Wolf D, Schüller H, Schild HH, Müdder T. Total body irradiation: Significant dose sparing of lung tissue achievable by helical tomotherapy. Z Med Phys. 2020 Feb;30(1):17-23.
Paix A, Antoni D, Waissi W, Ledoux MP, Bilger K, Fornecker L, Noel G. Total body irradiation in allogeneic bone marrow transplantation conditioning regimens: A review. Crit Rev Oncol Hematol. 2018 Mar;123:138-148.
Sarradin V, Simon L, Huynh A, Gilhodes J, Filleron T, Izar F. Total body irradiation using Helical Tomotherapy®: Treatment technique, dosimetric results and initial clinical experience. Cancer Radiother. 2018 Feb;22(1):17-24.
Gruen A, Ebell W, Wlodarczyk W, Neumann O, Kuehl JS, Stromberger C, Budach V, Marnitz S. Total Body Irradiation (TBI) using Helical Tomotherapy in children and young adults undergoing stem cell transplantation. Radiat Oncol. 2013 Apr 15;8:92.
Chao M, Penagaricano J, Yan Y, Moros EG, Corry P, Ratanatharathorn V. Voxel-based dose reconstruction for total body irradiation with helical tomotherapy. Int J Radiat Oncol Biol Phys. 2012 Apr 1;82(5):1575-83.

Videos

Russian Experience of using Helical TomoTherapy for Total Body Irradiation in Wide Heterogenic Cohort of 262 Pediatric Patients with Hematological Malignancies. Daria Kobyzeva M.D. & Anna Loginova M.S., Dmitry Rogachev National Medical Research Center, Moscow, Russia.

TomoTherapy Total Marrow Irradiation

Publications

Haraldsson A, Wichert S, Engström PE, Lenhoff S, Turkiewicz D, Warsi S, Engelholm S, Bäck S, Engellau J. Organ sparing total marrow irradiation compared to total body irradiation prior to allogeneic stem cell transplantation. Eur J Haematol. 2021 Jun 9.
Zuro D, Vagge S, Broggi S, Agostinelli S, Takahashi Y, Brooks J, Leszcynska P, Liu A, Zucchetti C, Saldi S, Han C, Cattaneo M, Giebel S, Mahe MA, Sanchez JF, Alaei P, Anna C, Dusenbery K, Pierini A, Storme G, Aristei C, Wong JYC, Hui S. Multi-institutional evaluation of MVCT guided patient registration and dosimetric precision in total marrow irradiation: A global health initiative by the international consortium of total marrow irradiation. Radiother Oncol. 2019 Dec;141:275-282.
Haraldsson A, Engellau J, Lenhoff S, Engelholm S, Bäck S, Engström PE. Implementing safe and robust Total Marrow Irradiation using Helical Tomotherapy – A practical guide. Phys Med. 2019 Apr;60:162-167. D
Paix A, Antoni D, Waissi W, Ledoux MP, Bilger K, Fornecker L, Noel G. Total body irradiation in allogeneic bone marrow transplantation conditioning regimens: A review. Crit Rev Oncol Hematol. 2018 Mar;123:138-148.
Kim JH, Stein A, Tsai N, Schultheiss TE, Palmer J, Liu A, Rosenthal J, Forman SJ, Wong JY. Extramedullary relapse following total marrow and lymphoid irradiation in patients undergoing allogeneic hematopoietic cell transplantation. Int J Radiat Oncol Biol Phys. 2014 May 1;89(1):75-81.
Takahashi Y, Hui SK. Fast, simple, and informative patient-specific dose verification method for intensity modulated total marrow irradiation with helical tomotherapy. Radiat Oncol. 2014 Jan 25;9:34.

Videos

From TBI to TMI for Advanced Onco-Hematological Diseases. Stefano Vagge M.D. Ph.D., IRCCS Policlinico San Martino, Genova, Italy.
Total Marrow Irradiation with TomoTherapy®: Redefining the Role of Radiation Therapy in Hematopoietic Cell Transplantation. Jeffrey Wong M.D. & An Liu Ph.D., City of Hope, Duarte, CA, USA.

Total Skin Irradiation

Publications

Haraldsson A, Engleson J, Bäck SÅJ, Engelholm S, Engström PE. A Helical tomotherapy as a robust low-dose treatment alternative for total skin irradiation. J Appl Clin Med Phys. 2019 May;20(5):44-54.
Hsieh CH, Tien HJ, Yu YB, Wu YH, Shueng PW, Lu YF, Wang SY, Wang LY. Simultaneous integrated boost with helical arc radiotherapy of total skin (HEARTS) to treat cutaneous manifestations of advanced, therapy-refractory cutaneous lymphoma and leukemia – dosimetry comparison of different regimens and clinical application. Radiat Oncol. 2019 Jan 28;14(1):17.
Hsieh CH, Shueng PW, Lin SC, Tien HJ, Shiau AC, Chou YH, Wu MH, Wang JY, Chen CK, Chen YJ. Helical irradiation of the total skin with dose painting to replace total skin electron beam therapy for therapy-refractory cutaneous CD4+ T-cell lymphoma. Biomed Res Int. 2013;2013:717589.

TomoTherapy Pediatrics

Publications

Lee J, Kim E, Kim N, Byun HK, Suh CO, Chung Y, Yoon HI. Practical aspects of the application of helical tomotherapy for craniospinal irradiation. Sci Rep. 2021 Mar 17;11(1):6120
Salfelder MA, Kessel KA, Thiel U, Burdach S, Kampfer S, Combs SE. Prospective evaluation of multitarget treatment of pediatric patients with helical intensity-modulated radiotherapy. Strahlenther Onkol. 2020 Dec;196(12):1103-1115.
Chen GY, Cheng JC, Chen YH, Lu MY, Chang HH, Yang YL, Jou ST, Hsu WM, Kuo SH. Local Control and Clinical Outcome of High-risk Pediatric Neuroblastoma Patients After Receiving Multimodality Treatment and Helical Tomotherapy. Anticancer Res. 2019 Apr;39(4):2207-2215.
Scobioala S, Parfitt R, Matulat P, Kittel C, Ebrahimi F, Wolters H, Am Zehnhoff-Dinnesen A, Eich HT. Impact of radiation technique, radiation fraction dose, and total cisplatin dose on hearing : Retrospective analysis of 29 medulloblastoma patients. Strahlenther Onkol. 2017 Nov;193(11):910-920.
Schiopu SR, Habl G, Häfner M, Katayama S, Herfarth K, Debus J, Sterzing F. Craniospinal irradiation using helical tomotherapy for central nervous system tumors. J Radiat Res. 2017 Mar 1;58(2):238-246.
Zhang X, Ma K, Wang J, Wu W, Ma L, Huang D. A prospective evaluation of the combined helical tomotherapy and chemotherapy in pediatric patients with unresectable rhabdomyosarcoma of the temporal bone. Cell Biochem Biophys. 2014 Sep;70(1):103-8.
Peñagarícano J, Moros E, Corry P, Saylors R, Ratanatharathorn V. Pediatric craniospinal axis irradiation with helical tomotherapy: patient outcome and lack of acute pulmonary toxicity. Int J Radiat Oncol Biol Phys. 2009 Nov 15;75(4):1155-61.

Videos/Slides

Russian Experience of using Helical TomoTherapy for Total Body Irradiation in Wide Heterogenic Cohort of 262 Pediatric Patients with Hematological Malignancies. Daria Kobyzeva M.D. & Anna Loginova M.S., Dmitry Rogachev National Medical Research Center, Moscow, Russia.
What Does the TomoTherapy® System Bring to Pediatric Treatment Challenges? Anne Laprie, M.D., Ph.D., IUCT Oncopole, Toulouse, France.
VLADI: An alternative to anesthesia in radiotherapy treatments. Ana Roma Calçarão, Cliniques Universitaires Saint-Luc, Brussels, Belgium.

Moving Targets Treatment

Motion Synchronization on CyberKnife

Publications

Nakayama M, Nishimura H, Mayahara H et al. Clinical log data analysis for assessing the accuracy of the CyberKnife fiducial-free lung tumor tracking system. Pract Radiat Oncol. 2018 Mar – Apr;8(2):e63-e70
Pepin EW, Wu H, Zhang Y, Lord B. Correlation and prediction uncertainties in the cyberknife synchrony respiratory tracking system. Med Phys. 2011 Jul;38(7):4036-44
Hoogeman M, Prévost JB, Nuyttens J, Pöll J, Levendag P, Heijmen B. Clinical accuracy of the respiratory tumor tracking system of the cyberknife: assessment by analysis of log files. Int J Radiat Oncol Biol Phys. 2009 May 1;74(1):297-303.

Videos

Dynamic Tracking and Motion Correction: Over 15 Years of Accuray Leadership featuring
- Clinical Value of Motion Synchronization for Lung SBRT. Jonathan W. Lischalk, M.D., Medstar Georgetown University Hospital, Washington, DC, USA.
- Clinical Value of Motion Synchronization for Prostate SBRT. Ronald Chen, M.D. M.P.H., University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
CyberKnife® System with Fiducial Tracking Mature Outcomes. Brian T. Collins, M.D., MedStar Georgetown University Hospital, Washington, DC, USA.
MyAccuray: Accuray Synchrony® Raises the Bar in AAPM MArkerless Lung Target Tracking Challenge. Lee Goddard, MPhys, DABR, Montefiore Medical Center in New York, NY and Andrea Cox, Ph.D., Senior Director, Brand Strategy, Accuray Incorporated
25 Years of SBRT with CyberKnife. Anand Mahadevan M.D. and Jimm Grimm Ph.D. Geisinger Medical Center, Danville, PA, USA.

For more indication specific information, please click here.

Motion Synchronization on Radixact

Publications

Goddard L, Jeong K, Tomé WA. Commissioning and routine quality assurance of the Radixact Synchrony system. Med Phys. 2021 Dec 16.
Ferris WS, Culberson WS. Technical Note: Patient dose from kilovoltage radiographs during motion-synchronized treatments on Radixact^®. Med Phys. 2020 Nov;47(11):5772-5778.
Ferris WS, Kissick MW, Bayouth JE, Culberson WS, Smilowitz JB. Evaluation of radixact motion synchrony for 3D respiratory motion: Modeling accuracy and dosimetric fidelity. J Appl Clin Med Phys. 2020 Sep;21(9):96-106.
Chen GP, Tai A, Keiper TD, Lim S, Li XA. Technical Note: Comprehensive performance tests of the first clinical real-time motion tracking and compensation system using MLC and jaws. Med Phys. 2020 Jul;47(7):2814-2825.
Price A, Chen J, Chao E, Schnarr E, Schreiber E, Lu L, Cox A, Chang S, Jian J. Compensation of intrafractional motion for lung stereotactic body radiotherapy (SBRT) on helical TomoTherapy. Phys. Eng. Express 2019;5:025043.
Schnarr E, Beneke M, Casey D, Chao E, Chappelow J, Cox A, Henderson D, Jordan P, Lessard E, Lucas D, Myronenko A, Mauer C. Feasibility of real-time motion management with helical tomotherapy. Med Phys. 2018 Apr;45(4):1329-1337.
Chao EH, Lucas D, Schnarr E. Evaluation of TomoTherapy dose calculations with intrafractional motion and motion compensation. Med Phys. 2018 Jan;45(1):18-28.

Videos

MyAccuray: Accuray Synchrony® Raises the Bar in AAPM MArkerless Lung Target Tracking Challenge. Lee Goddard, MPhys, DABR, Montefiore Medical Center in New York, NY and Andrea Cox, Ph.D., Senior Director, Brand Strategy, Accuray Incorporated
Comprehensive Performance Tests of the First Clinical Real-Time Motion Tracking and Compensation System Using MLC and Jaws. Guang-Pei Chen Ph.D., Medical College of Wisconsin, Milwaukee, WI, USA.
Dynamic Tracking and Motion Correction: Over 15 Years of Accuray Leadership featuring
- QA Testing of Motion Tracking with Synchrony®. X. Allen Li, Ph.D., DABMP, FAAPM, Medical College of Wisconsin, Milwaukee, WI, USA.
Validating Synchrony® on the Radixact® System for Respiratory Motion. John E. Bayouth, Ph.D., UW-Madison School of Medicine and Public Health, Madison, WI, USA.

SBRT Treatment

CyberKnife Head and Neck

Publications

Hong S, Kagawa K, Sato K, Ichi S. The Long-Term Outcome of CyberKnife-Based Stereotactic Radiotherapy for Head and Neck Paragangliomas: A Single-Center Experience. World Neurosurg. 2021 Nov;155:e382-e390.
Blažek T, Zděblová Čermáková Z, Knybel L, Hurník P, Štembírek J, Resová K, Paračková T, Formánek M, Cvek J, Soumarová R. Dose escalation in advanced floor of the mouth cancer: a pilot study using a combination of IMRT and stereotactic boost. Radiat Oncol. 2021 Jun 29;16(1):122.
Kobayashi D, Sato H, Saitoh JI, Oike T, Nakajima A, Noda SE, Kato S, Iwanaga M, Shimizu T, Nakano T. Efficacy and Feasibility of Salvage Re-Irradiation with CyberKnife for In-Field Neck Lymph Node Recurrence: A Retrospective Study. J Clin Med. 2019 Nov 7;8(11):1911
Tosun İ, Atalar B, Şahin B, Güngör G, Aydin G, Yapici B, Özyar E. Robotic radiosurgery of head and neck paragangliomas: a single institution experience. Asia Pac J Clin Oncol. 2018 Apr;14(2):e3-e7.
Marchetti M, Pinzi V, Tramacere I, Bianchi LC, Ghielmetti F, Fariselli L. Radiosurgery for Paragangliomas of the Head and Neck: Another Step for the Validation of a Treatment Paradigm.World Neurosurg. 2017 Feb;98:281-287.
Kress MA, Sen N, Unger KR, Lominska CE, Deeken JF, Davidson BJ, Newkirk KA, Hwang J, Harter KW. Safety and efficacy of hypofractionated stereotactic body reirradiation in head and neck cancer: Long-term follow-up of a large series. Head Neck. 2015 Oct;37(10):1403-9.
Bonomo P, Cipressi S, Iermano C, Bonucci I, Masi L, Doro R, Favuzza V, Paiar F, Simontacchi G, Meattini I, Greto D, Agresti B, Livi L, Biti G. Salvage stereotactic re-irradiation with CyberKnife for locally recurrent headand neck cancer: a single center experience. Tumori. 2014 May-Jun;100(3):278-83

CyberKnife Ocular

Publications

Schmelter V, Heidorn S, Muacevic A, Priglinger SG, Foerster P, Liegl R. Robotic assisted CyberKnife radiosurgery for the treatment of iris melanoma. Sci Rep. 2021 Mar 11;11(1):5685.
Siedlecki J, Reiterer V, Leicht S, Foerster P, Kortüm K, Schaller U, Priglinger S, Fuerweger C, Muacevic A, Eibl-Lindner K. Incidence of secondary glaucoma after treatment of uveal melanoma with robotic radiosurgery versus brachytherapy. Acta Ophthalmol. 2017 Dec;95(8):e734-e739.
Yazici G, Kiratli H, Ozyigit G, Sari SY, Cengiz M, Tarlan B, Mocan BO, Zorlu F. Stereotactic Radiosurgery and Fractionated Stereotactic Radiation Therapy for the Treatment of Uveal Melanoma. Int J Radiat Oncol Biol Phys. 2017 May 1;98(1):152-158.
Choi SY, Kim MS, Yoo SY, Cho CK, Lhee CH, Lee DH, Kang JK, Shin YJ. Feasibility of image-guided robotic radiotherapy using three fractions for uveal melanoma. Tumori. 2009 Nov-Dec;95(6):720-5.

CyberKnife Breast

Publications

Lemoine P, Bruand M, Kammerer E, Bogart E, Comte P, Royer P, Thariat J, Pasquier D. Stereotactic Body Radiation Therapy for Oligometastatic Breast Cancer: A Retrospective Multicenter Study. Front Oncol. 2021 Oct 28;11:736690.
Rahimi A, Morgan HE, Kim DW, Zhang Y, Leitch M, Wooldridge R, Goudreau S, Haley B, Rao R, Rivers A, Spangler AE, Jones RT, Stevenson S, Staley J, Albuquerque K, Ahn C, Neufeld S, Alluri PG, Ding C, Garwood D, Seiler S, Zhao B, Gu X, Timmerman R. Cosmetic Outcomes of a Phase 1 Dose Escalation Study of 5-Fraction Stereotactic Partial Breast Irradiation for Early Stage Breast Cancer. Int J Radiat Oncol Biol Phys. 2021 Jul 1;110(3):772-782.
Rahimi A, Zhang Y, Kim DW, Morgan H, Hossain F, Leitch M, Wooldridge R, Seiler S, Goudreau S, Haley B, Rao R, Rivers A, Spangler A, Ahn C, Stevenson S, Staley J, Albuquerque K, Ding C, Gu X, Zhao B, Timmerman R. Risk Factors for Fat Necrosis After Stereotactic Partial Breast Irradiation for Early-Stage Breast Cancer in a Phase 1 Clinical Trial. Int J Radiat Oncol Biol Phys. 2020 Nov 1;108(3):697-706.
Mészáros N, Smanykó V, Major T, Stelczer G, Jánváry L, Kovács E, Mária B, Zaka Z, Pukancsik D, Takácsi-Nagy Z, Polgár C. Implementation of Stereotactic Accelerated Partial Breast Irradiation Using Cyber-Knife – Technical Considerations and Early Experiences of a Phase II Clinical Study. Pathol Oncol Res. 2020 Oct;26(4):2307-2313.
Lee WH, Chang JS, Kim MJ, Park VY, Yoon JH, Kim SY, Kim JY, Park HS, Kim SI, Cho YU, Park BW, Kim YB. First Experience in Korea of Stereotactic Partial Breast Irradiation for Low-Risk Early-Stage Breast Cancer. Front Oncol. 2020 Apr 29;10:672.
Rahimi A, Thomas K, Spangler A, Rao R, Leitch M, Wooldridge R, Rivers A, Seiler S, Albuquerque K, Stevenson S, Goudreau S, Garwood D, Haley B, Euhus D, Heinzerling J, Ding C, Gao A, Ahn C, Timmerman R. Preliminary Results of a Phase 1 Dose-Escalation Trial for Early-Stage Breast Cancer Using 5-Fraction Stereotactic Body Radiation Therapy for Partial-Breast Irradiation. Int J Radiat Oncol Biol Phys. 2017 May 1;98(1):196-205.e2.
Seiler S, Rahimi A, Choudhery S, Garwood D, Spangler A, Cherian S, Goudreau S. Ultrasound-Guided Placement of Gold Fiducial Markers for Stereotactic Partial-Breast Irradiation. AJR Am J Roentgenol. 2016 Sep;207(3):685-8.

Videos

CyberKnife® System Experience for Partial Breast Irradiation. Asal Rahimi M.D. M.S., UT Southwestern Medical Center, Dallas, TX, USA.

CyberKnife Lung

Publications

Abe T, Ryuno Y, Iino M, Saito S, Aoshika T, Ohta T, Igari M, Hirai R, Kumazaki Y, Kaira K, Kagamu H, Ishida H, Noda SE, Kato S. A 54 Gy in three fractions of stereotactic body radiotherapy using CyberKnife for T1b-2aN0M0 pathologically confirmed non-small cell lung cancer. Jpn J Clin Oncol. 2021 Dec 1;51(12):1723-1728.
Sumodhee S, Bondiau PY, Poudenx M, Cohen C, Naghavi AO, Padovani B, Maneval D, Gal J, Leysalle A, Ghalloussi H, Otto J, Doyen J. Long term efficacy and toxicity after stereotactic ablative reirradiation in locally relapsed stage III non-small cell lung cancer. BMC Cancer. 2019 Apr 3;19(1):305.
Sharma A, Duijm M, Oomen-de Hoop E, Aerts JG, Verhoef C, Hoogeman M, Nuyttens JJ. Factors affecting local control of pulmonary oligometastases treated with stereotactic body radiotherapy. Acta Oncol. 2018 Aug;57(8):1031-1037.
Repka MC, Aghdam N, Kataria SK, Campbell L, Suy S, Collins SP, Anderson E, Lischalk JW, Collins BT. Five-fraction SBRT for ultra-central NSCLC in-field recurrences following high-dose conventional radiation. Radiat Oncol. 2017 Oct 19;12(1):162.
Lischalk JW, Malik RM, Collins SP, Collins BT, Matus IA, Anderson ED. Stereotactic body radiotherapy (SBRT) for high-risk central pulmonary metastases. Radiat Oncol. 2016 Feb 27;11:28.

Videos

A Location Dependent Strategy for Treating Lung Tumors with the CyberKnife® System. Cristian Cotrutz, PhD, Swedish Radiosurgery Center, Seattle, WA, USA.
Real-time Tumor Tracking for Lung Cancer: 12 Years of Clinical Outcomes with the CyberKnife® System. Jonathan W. Lischalk, M.D., Medstar Georgetown University Hospital, Washington, DC, USA.
Tips and Tricks to Treat Central Lung Tumors with the CyberKnife® System. Joost Nuyttens M.D., Erasmus Medical Center, Rotterdam, the Netherlands.

CyberKnife Liver

Publications

Sun J, Li WG, Wang Q, He WP, Wang HB, Han P, Zhang T, Zhang AM, Fan YZ, Sun YZ, Duan XZ. Hepatic Resection Versus Stereotactic Body Radiation Therapy Plus Transhepatic Arterial Chemoembolization for Large Hepatocellular Carcinoma: A Propensity Score Analysis. J Clin Transl Hepatol. 2021 Oct 28;9(5):672-681.
Dutta D, Tatineni T, Yarlagadda S, Gupte A, Reddy SK, Madhavan R, Nair H, Sasidharan A, Kannan R, Pottayil SG, Holla R, Sudhindran S. Hepatocellular carcinoma patients with portal vein thrombosis treated with robotic radiosurgery: Interim results of a prospective study. Indian J Gastroenterol. 2021 Aug;40(4):389-401.
Memon B, Kadri S, Sultana N, Saeed K, Ahmed N, Mahmood T. Cyberknife Radiosurgery in Hepatocellular Carcinoma. J Coll Physicians Surg Pak. 2021 May;30(5):532-536.
Que J, Lin CH, Lin LC, Ho CH. Challenges of BCLC stage C hepatocellular carcinoma: Results of a single-institutional experience on stereotactic body radiation therapy. Medicine (Baltimore). 2020 Aug 7;99(32):e21561.
Anstadt EJ, Shumway R, Colasanto J, Grew D. Single community-based institutional series of stereotactic body radiation therapy (SBRT) for treatment of liver metastases. J Gastrointest Oncol. 2019 Apr;10(2):330-338.
Stintzing S, Einem JV, Fueweger C, Haidenberger A, Fedorov M, Muavcevic A. Long-term Survival in Patients Treated with a Robotic Radiosurgical Device for Liver Metastases. Cancer Res Treat. 2019 Jan;51(1):187-193.
Yoon K, Kwak J, Cho B, Park JH, Yoon SM, Lee SW, Kim JH. Gated Volumetric-Modulated Arc Therapy vs. Tumor-Tracking CyberKnife Radiotherapy as Stereotactic Body Radiotherapy for Hepatocellular Carcinoma: A Dosimetric Comparison Study Focused on the Impact of Respiratory Motion Managements. PLoS One. 2016 Nov 22;11(11):e0166927.

Videos

Gated volumetric-modulated arc therapy vs. Tumor-tracking cyberknife radiotherapy as stereotactic body radiotherapy for hepatocellular carcinoma: a dosimetric comparison study focused on the impact of respiratory motion managements. Kyoung Jun Yoon, M.D., Byungchul Cho, M.D., Sang Min Yoon, M.D., Asan Medical Center, Seoul, South Korea.
CyberKnife® Experience for the Treatment of Liver Metastases in a Community Hospital. David J. Grew, M.D., Saint Francis Hospital and Medical Center, Hartford, CT, USA.
New Evidence for Hepatocellular Carcinoma SBRT Treatment with the CyberKnife® System. Yongchun Song, M.D., Ph.D., Tianjin Medical University Cancer Institute & Hospital, Tianjin, China

CyberKnife Pancreas

Publications

Shen ZT, Zhou H, Li AM, Ji XQ, Jiang CC, Yuan X, Li B, Zhu XX, Huang GC. Clinical outcomes and prognostic factors of stereotactic body radiation therapy combined with gemcitabine plus capecitabine for locally advanced unresectable pancreatic cancer. J Cancer Res Clin Oncol. 2020 Feb;146(2):417-428.
Lischalk JW, Burke A, Chew J, Elledge C, Gurka M, Marshall J, Pishvaian M, Collins S, Unger K. Five-Fraction Stereotactic Body Radiation Therapy (SBRT) and Chemotherapy for the Local Management of Metastatic Pancreatic Cancer. J Gastrointest Cancer. 2018 Jun;49(2):116-123.
Dagoglu N, Callery M, Moser J, Tseng J, Kent T, Bullock A, Miksad R, Mancias JD, Mahadevan A. Stereotactic Body Radiotherapy (SBRT) Reirradiation for Recurrent Pancreas Cancer. J Cancer. 2016 Jan 10;7(3):283-8.

Videos

Treatment of Pancreas Cancer with the CyberKnife® System. Anand Mahadevan M.D., Geisinger Medical Center, Danville, Pennsylvania, USA.
Re-irradiation with SBRT for Pancreatic Cancer. Zhang, Huo Jun, M.D., Ph.D. CyberKnife Center, Changhai Hospital, China.

CyberKnife Kidney

Publications

Senger C, Conti A, Kluge A, Pasemann D, Kufeld M, Acker G, Lukas M, Grün A, Kalinauskaite G, Budach V, Waiser J, Stromberger C. Robotic stereotactic ablative radiotherapy for renal cell carcinoma in patients with impaired renal function. BMC Urol. 2019 Oct 21;19(1):96.
S Kaidar-Person O, Price A, Schreiber E, Zagar TM, Chen RC. Stereotactic Body Radiotherapy for Large Primary Renal Cell Carcinoma. Clin Genitourin Cancer. 2017 Oct;15(5):e851-e854.
Ponsky L, Lo SS, Zhang Y, Schluchter M, Liu Y, Patel R, Abouassaly R, Welford S, Gulani V, Haaga JR, Machtay M, Ellis RJ. Phase I dose-escalation study of stereotactic body radiotherapy (SBRT) for poor surgical candidates with localized renal cell carcinoma. Radiother Oncol. 2015 Oct;117(1):183-7.
Staehler M, Bader M, Schlenker B, Casuscelli J, Karl A, Roosen A, Stief CG, Bex A, Wowra B, Muacevic A. Single fraction radiosurgery for the treatment of renal tumors. J Urol. 2015 Mar;193(3):771-5.

CyberKnife Prostate

Publications

Zhao X, Ye Y, Yu H, Jiang L, Cheng C, Guo X, Ju X, Zhu X, Zhang H. Five-year outcomes of stereotactic body radiation therapy (SBRT) for prostate cancer: the largest experience in China. J Cancer Res Clin Oncol. 2021 Dec;147(12):3557-3564. doi: 10.1007/s00432-021-03785-2. Epub 2021 Sep 15.
Pepin A, Shah S, Pernia M, Lei S, Ayoob M, Danner M, Yung T, Collins BT, Suy S, Aghdam N, Collins SP. Bleeding Risk Following Stereotactic Body Radiation Therapy for Localized Prostate Cancer in Men on Baseline Anticoagulant or Antiplatelet Therap Front Oncol. 2021 Sep 17;11:722852.
Jorgo K, Polgar C, Stelczer G, Major T, Gesztesi L, Agoston P. Acute side effects after definitive stereotactic body radiation therapy (SBRT) for patients with clinically localized or locally advanced prostate cancer: a single institution prospective study. Radiol Oncol. 2021 Jul 13;55(4):474-481.
Ricco A, Barbera G, Lanciano R, Feng J, Hanlon A, Lozano A, Good M, Arrigo S, Lamond J, Yang J. Favorable Biochemical Freedom From Recurrence With Stereotactic Body Radiation Therapy for Intermediate and High-Risk Prostate Cancer: A Single Institutional Experience With Long-Term Follow-Up. Front Oncol. 2020 Sep 25;10:1505.
Fuller DB, Naitoh J, Shirazi R, Crabtree T, Mardirossian G. Prostate SBRT: Comparison the Efficacy and Toxicity of Two Different Dose Fractionation Schedules. Front Oncol. 2020 Jun 25;10:936.
Brand DH, Tree AC, Ostler P, van der Voet H, Loblaw A, Chu W, Ford D, Tolan S, Jain S, Martin A, Staffurth J, Camilleri P, Kancherla K, Frew J, Chan A, Dayes IS, Henderson D, Brown S, Cruickshank C, Burnett S, Duffton A, Griffin C, Hinder V, Morrison K, Naismith O, Hall E, van As N; PACE Trial Investigators. Intensity-modulated fractionated radiotherapy versus stereotactic body radiotherapy for prostate cancer (PACE-B): acute toxicity findings from an international, randomised, open-label, phase 3, non-inferiority trial. Lancet Oncol. 2019 Nov;20(11):1531-1543.
Blacksburg SR, Aghdam N, Royce TJ, Burri RJ, Obayomi-Davies O, Mezeckis M, Meier R, Fuller DB, Chen RC, Lanciano RM, Haas JA, Collins SP. 5-year Biochemical Outcomes of Stereotactic Body Radiotherapy with Intraprostatic Dose Escalation for Unfavorable Prostate Cancer. Int J Radiat Oncol Biol Phys. 2019 Sep 8;105(1):E263–E264 (ASTRO 2019)
Wang K, Chen RC, Kane B, Medbery CA, Underhill K, Gray JR, Peddada AV, Fuller DB. Patient and Dosimetric Predictors of Genitourinary and Bowel Quality of Life After Prostate SBRT: Secondary Analysis of a Multi-institutional Trial. Int J Radiat Oncol Biol Phys. 2018 Dec 1;102(5):1430-1437
Meier RM, Bloch DA, Cotrutz C, Beckman AC, Henning GT, Woodhouse SA, Williamson SK, Mohideen N, Dombrowski JJ, Hong RL, Brachman DG, Linson PW, Kaplan ID. Multicenter Trial of Stereotactic Body Radiation Therapy for Low- and Intermediate-Risk Prostate Cancer: Survival and Toxicity Endpoints. Int J Radiat Oncol Biol Phys. 2018 Oct 1;102(2):296-303.

Videos

Intensity-Modulated Fractionated Radiotherapy versus Stereotactic Body Radiotherapy for Prostate Cancer (PACE-B): Acute Toxicity Findings from an International, Randomised, Open-Label, Phase 3, Non-Inferiority Trial. Nicholas van As M.D., Royal Marsden Hospital, London, UK.
SBRT as a Salvage Option for Localized Recurrent Prostate Cancer. Donald Fuller M.D., Genesis Healthcare Partners, San Diego, CA, USA.
CyberKnife®: the Effect of Intrafraction Rotation as a Predictor of Rectal Toxicity in Prostate SBRT. Seth Blacksburg, M.D., Winthrop Radiology Associates, Mineola, NY, USA.
Building a Prostate SBRT Program with the CyberKnife® System. Jonathan A. Haas M.D., Winthrop University Hospital, Mineola, NY, USA.
CyberKnife® SBRT for Prostate Cancer: Is 5 better than 44? Olusola Obayomi-Davies M.D., Philadelphia CyberKnife/Crozer Keystone Health System, Havertown, PA, USA.

CyberKnife Gynecological

Publications

Kataria T, Naga P, Banerjee S, Gupta D, Narang K, Tayal M, Bisht SS. CyberKnife Stereotactic Ablative Radiotherapy for Recurrent or Oligometastatic Gynecological Cancers. South Asian J Cancer. 2021 Apr;10(2):107-111. doi: 10.1055/s-0041-1731576. Epub 2021 Jul 4.
Morgenthaler J, Köhler C, Budach V, Sehouli J, Stromberger C, Besserer A, Trommer M, Baues C, Marnitz S. Long-term results of robotic radiosurgery for non brachytherapy patients with cervical cancer. Strahlenther Onkol. 2021 Jun;197(6):474-486.
Pontoriero A, Iatì G, Aiello D, Pergolizzi S. Stereotactic Radiotherapy in the Retreatment of Recurrent Cervical Cancers, Assessment of Toxicity, and Treatment Response: Initial Results and Literature Review. Technol Cancer Res Treat. 2016 Dec;15(6):759-765.
Park HJ, Chang AR, Seo Y, Cho CK, Jang WI, Kim MS, Choi C. Stereotactic Body Radiotherapy for Recurrent or Oligometastatic Uterine Cervix Cancer: A Cooperative Study of the Korean Radiation Oncology Group (KROG 14-11). Anticancer Res. 2015 Sep;35(9):5103-10.
Kunos CA, Sherertz TM, Mislmani M, Ellis RJ, Lo SS, Waggoner SE, Zanotti KM, Herrmann K, Debernardo RL. Phase I Trial of Carboplatin and Gemcitabine Chemotherapy and Stereotactic Ablative Radiosurgery for the Palliative Treatment of Persistent or Recurrent Gynecologic Cancer. Front Oncol. 2015 Jun 5;5:126.

CyberKnife Sarcoma

Publications

Sallabanda M, Garcia R, Lorenzana L, Santaolalla I, Abarca J, Sallabanda K. Treatment of Chordomas and Chondrosarcomas With CyberKnife Robotic Hypofractionated Radiosurgery: A Single Institution Experience. Cureus. 2021 Aug 8;13(8):e17012.
Baumann BC, Nagda SN, Kolker JD, Levin WP, Weber KL, Berman AT, Staddon A, Hartner L, Hahn SM, Glatstein E, Simone CB 2nd. Efficacy and safety of stereotactic body radiation therapy for the treatment of pulmonary metastases from sarcoma: A potential alternative to resection. J Surg Oncol. 2016 Jul;114(1):65-9.

TomoTherapy Lung

Publications

Okada W, Doi H, Tanooka M, Sano K, Nakamura K, Sakai Y, Shibata M, Tanaka M. A first report of tumour-tracking radiotherapy with helical tomotherapy for lung and liver tumours: A double case report. SAGE Open Med Case Rep. 2021 Jun 12;9:2050313X211023688.
Scotti V, Bruni A, Francolini G, Perna M, Vasilyeva P, Loi M, Simontacchi G, Viggiano D, Lanfranchi B, Gonfiotti A, Topulli J, Olmetto E, Maragna V, Ferrari K, Bonti V, Comin C, Balduzzi S, D’Amico R, Lohr F, Voltolini L, Livi L. Stereotactic Ablative Radiotherapy as an Alternative to Lobectomy in Patients With Medically Operable Stage I NSCLC: A Retrospective, Multicenter Analysis. Clin Lung Cancer. 2019 Jan;20(1):e53-e61.

TomoTherapy Mesothelioma

Publications

Parisi E, Romeo A, Sarnelli A, Ghigi G, Bellia SR, Neri E, Micheletti S, Dipalma B, Arpa D, Furini G, Burgio MA, Genestreti G, Gurioli C, Sanna S, Bovolato P, Rea F, Storme G, Scarpi E, Arienti C, Tesei A, Polico R. High dose irradiation after pleurectomy/decortication or biopsy for pleural mesothelioma treatment. Cancer Radiother. 2017 Dec;21(8):766-773.

TomoTherapy Liver

Publications

Chen YX, Zhuang Y, Yang P, Fan J, Zhou J, Hu Y, Zhu WC, Sun J, Zeng ZC. Helical IMRT-Based Stereotactic Body Radiation Therapy Using an Abdominal Compression Technique and Modified Fractionation Regimen for Small Hepatocellular Carcinoma. Technol Cancer Res Treat. 2020 Jan-Dec;19:1533033820937002.

SRS Treatment

CyberKnife for Brain Metastases

Publications

Borzillo V, Di Franco R, Giannarelli D, Cammarota F, Scipilliti E, D’Ippolito E, Petito A, Serra M, Falivene S, Grimaldi AM, Simeone E, Festino L, Vanella V, Trojaniello C, Vitale MG, Madonna G, Ascierto PA, Muto P. Ipilimumab and Stereotactic Radiosurgery with CyberKnife^® System in Melanoma Brain Metastases: A Retrospective Monoinstitutional Experience. Cancers (Basel). 2021 Apr 13;13(8):1857.
Berber T, Raturi V, Aksaray F, Hojo H, Fujisawa T, Ohyoshi H. Clinical outcome after CyberKnife® radiosurgery re-irradiation for recurrent brain metastases. Cancer Radiother. 2021 Mar 19:S1278-3218(21)00028-7.
El Shafie RA, Celik A, Weber D, Schmitt D, Lang K, König L, Bernhardt D, Höne S, Forster T, von Nettelbladt B, Adeberg S, Debus J, Rieken S. A matched-pair analysis comparing stereotactic radiosurgery with whole-brain radiotherapy for patients with multiple brain metastases. J Neurooncol. 2020 May;147(3):607-618.
Jiang X, Wang H, Song Y, Wang X, Li F, Dong Y, Wang J, Chen H, Yuan Z. A Second Course of Stereotactic Image-Guided Robotic Radiosurgery for Patients with Cerebral Metastasis. World Neurosurg. 2019 Mar;123:e621-e628.
Martinage G, Geffrelot J, Stefan D, Bogart E, Rault E, Reyns N, Emery E, Makhloufi-Martinage S, Mouttet-Audouard R, Basson L, Mirabel X, Lartigau E, Pasquier D. Efficacy and Tolerance of Post-operative Hypo-Fractionated Stereotactic Radiotherapy in a Large Series of Patients With Brain Metastases. Front Oncol. 2019 Mar 28;9:184.
Lohkamp LN, Vajkoczy P, Budach V, Kufeld M. Efficacy, safety and outcome of frameless image-guided robotic radiosurgery for brain metastases after whole brain radiotherapy. J Neurooncol. 2018 May;138(1):73-81.
Sharpton SR, Oermann EK, Moore DT, Schreiber E, Hoffman R, Morris DE, Ewend MG. The volumetric response of brain metastases after stereotactic radiosurgery and its post-treatment implications. 2014 Jan;74(1):9-16.

Videos

Multifraction SRS in the Treatment of Large Brain Oligometastases. Huaguang Zhu M.D., Huashan Hospital, Shanghai, China.
Multiple Brain Metastases: The Stanford CyberKnife® Experience. Erqi Pollom, M.D., M.S, Stanford University, Stanford, CA, USA.
The Impact of 1-3 vs ≥ 4 Brain Metastases and Patient, Tumor and Imaging Parameters on Overall Survival after CyberKnife® Radiosurgery. Judith A. Murovic, MD, Stanford Medical Center, Stanford, CA, USA.
Planning for Multiple Brain Metastases with the CyberKnife® System. Daniela Schmitt Ph.D., Heidelberg University Hospital, Germany.
Planning with the CyberKnife® VOLO™ Optimizer: Hear from the experts. Dr Reynolds, Minnesota Oncology, Mr Ozeroglu, Las Vegas CyberKnife, Dr Witten, NYU Langone Hospital, Long Island, NY, USA.

CyberKnife Other Malignant Tumors

Publications

Nguyen EK, Pond GR, Greenspoon JN, Whitton AC, Hann C. Hypofractionated Stereotactic Radiotherapy for the Treatment of Benign Intracranial Meningiomas: Long-Term Safety and Efficacy. Curr Oncol. 2021 Sep 23;28(5):3683-3691.
Fatima N, Meola A, Ding VY, Pollom E, Soltys SG, Chuang CF, Shahsavari N, Hancock SL, Gibbs IC, Adler JR, Chang SD.J . The Stanford stereotactic radiosurgery experience on 7000 patients over 2 decades (1999-2018): looking far beyond the scalpel. Neurosurg. 2021 Apr 2:1-17
Senger C, Kluge A, Kord M, Zimmermann Z, Conti A, Kufeld M, Kreimeier A, Loebel F, Stromberger C, Budach V, Vajkoczy P, Acker G. Effectiveness and Safety of Robotic Radiosurgery for Optic Nerve Sheath Meningiomas: A Single Institution Series. Cancers (Basel). 2021 Apr 30;13(9):2165.
Hong S, Sato K, Kagawa K, Ichi S. The long-term outcome of CyberKnife-based stereotactic radiotherapy for central skull base meningiomas: a single-center experience. Neurosurg Rev. 2021 Apr 10.
Ehret F, Kufeld M, Fürweger C, Haidenberger A, Windisch P, Senger C, Kord M, Träger M, Kaul D, Schichor C, Tonn JC, Muacevic A. Image-Guided Robotic Radiosurgery for the Management of Spinal Ependymomas. Front Oncol. 2021 Apr 29;11:654251. doi: 10.3389/fonc.2021.654251
Huang L, Bai J, Zhang Y, Cui Z, Zhang Z, Li J, Wang J, Yu X, Ling Z, Qu B, Pan L. Treatment of Residual, Recurrent, or Metastatic Intracranial Hemangiopericytomas With Stereotactic Radiotherapy Using CyberKnife. Front Oncol. 2021 Mar 3;11:577054.
De Maria L, Terzi di Bergamo L, Conti A, Hayashi K, Pinzi V, Murai T, Lanciano R, Burneikiene S, Buglione di Monale M, Magrini SM, Fontanella MM. CyberKnife for Recurrent Malignant Gliomas: A Systematic Review and Meta-Analysis. Front Oncol. 2021 Mar 29;11:652646.
Conti A, Pontoriero A, Iatì G, Cardali SM, Brogna A, Friso F, Rosetti V, Zoli M, Parisi S, Cacciola A, Lillo S, Pergolizzi S, Mazzatenta D. Image-Guided Multisession Radiosurgery of Skull Base Meningiomas. Cancers (Basel). 2020 Nov 29;12(12):E3569.
Oh HJ, Cho YH, Kim JH, Kim CJ, Kwon DH, Lee D, Yoon K.J Hypofractionated stereotactic radiosurgery for large-sized skull base meningiomas. Neurooncol. 2020 Aug;149(1):87-93.
Conti A, Senger C, Acker G, Kluge A, Pontoriero A, Cacciola A, Pergolizzi S, Germanò A, Badakhshi H, Kufeld M, Meinert F, Nguyen P, Loebel F, Vajkoczy P, Budach V, Kaul D. Normofractionated stereotactic radiotherapy versus CyberKnife-based hypofractionation in skull base meningioma: a German and Italian pooled cohort analysis. Radiat Oncol. 2019 Nov 12;14(1):201.
Marchetti M, Conti A, Beltramo G, Pinzi V, Pontoriero A, Tramacere I, Senger C, Pergolizzi S, Fariselli L. Multisession radiosurgery for perioptic meningiomas: medium-to-long term results from a CyberKnife cooperative study. J Neurooncol. 2019 Jul;143(3):597-604
Zhang J, Liu Q, Yuan Z, Zhao L, Wang X, Wang P. Clinical Efficacy of CyberKnife Radiosurgery for Adult Brainstem Glioma: 10 Years Experience at Tianjin CyberKnife Center and Review of the Literature. Front Oncol. 2019 Apr 12;9:257.
Repka MC, Lei S, Campbell L, Suy S, Voyadzis JM, Kalhorn C, McGrail K, Jean W, Subramaniam DS, Lischalk JW, Collins SP, Collins BT. Long-Term Outcomes Following Conventionally Fractionated Stereotactic Boost for High-Grade Gliomas in Close Proximity to Critical Organs at Risk. Front Oncol. 2018 Sep 11;8:373.
Yazici O, Guzle Adas Y, Kekilli E, Calikoglu T, Bedri Altundag M, Riza Ucer A, Ertas G, Durmus Duzgun S, Ozbagi K, Demirkasimoglu A, Demir E, Aslan B, Kaya B. Intracranial meningioma: Experience with stereotactic radiotherapy. J BUON. 2018 Jul-Aug;23(4):1169-1173.
Zhang M, Ho AL, D’Astous M, Pendharkar AV, Choi CY, Thompson PA, Tayag AT, Soltys SG, Gibbs IC, Chang SD. CyberKnife Stereotactic Radiosurgery for Atypical and Malignant Meningiomas. World Neurosurg. 2016 Jul;91:574-581.e1.
Pinzi V, Orsi C, Marchetti M, Milanesi IM, Bianchi LC, DiMeco F, Cuccarini V, Farinotti M, Ferroli P, Finocchiaro G, Franzini A, Fumagalli M, Silvani A, Fariselli L. Radiosurgery reirradiation for high-grade glioma recurrence: a retrospective analysis. Neurol Sci. 2015 Aug;36(8):1431-40.
Oermann EK, Bhandari R, Chen VJ, Lebec G, Gurka M, Lei S, Chen L, Suy S, Azumi N, Berkowitz F, Kalhorn C, McGrail K, Collins BT, Jean WC, Collins SP. Five fraction image-guided radiosurgery for primary and recurrent meningiomas. Front Oncol. 2013 Aug 20;3:213.

Videos

Glioblastoma re-irradiation with the CyberKnife® System. Frédéric Dhermain M.D., Ph.D. (Radiation Oncologist) and Sarah Dumont M.D., Ph.D. (Medical Oncologist), Gustave Roussy University Hospital, Villejuif, France.

CyberKnife Benign Tumors

Publications

Puataweepong P, Dhanachai M, Swangsilpa T, Sitathanee C, Ruangkanchanasetr R, Hansasuta A, Pairat K. Long-term clinical outcomes of stereotactic radiosurgery and hypofractionated stereotactic radiotherapy using the CyberKnife® robotic radiosurgery system for vestibular schwannoma. Asia Pac J Clin Oncol. 2021 Jul 26.
Pialat PM, Fieux M, Tringali S, Beldjoudi G, Pommier P, Tanguy R. Vestibular Schwannoma: Results of Hypofractionated Stereotactic Radiation Therapy. Adv Radiat Oncol. 2021 Mar 23;6(4):100694.
Windisch PY, Tonn JC, Fürweger C, Wowra B, Kufeld M, Schichor C, Muacevic A. Clinical Results After Single-fraction Radiosurgery for 1,002 Vestibular Schwannomas. Cureus. 2019 Dec 16;11(12):e6390.
Przybylowski CJ, Baranoski JF, Paisan GM, Chapple KM, Meeusen AJ, Sorensen S, Almefty KK, Porter RW. CyberKnife radiosurgery for acoustic neuromas: Tumor control and clinical outcomes. J Clin Neurosci. 2019 May;63:72-76.
Casentini L, Fornezza U, Perini Z, Perissinotto E, Colombo F. Multisession stereotactic radiosurgery for large vestibular schwannomas. J Neurosurg. 2015 Apr;122(4):818-24.

Videos

Clinical Results After Single-fraction Radiosurgery for 1,002 Vestibular Schwannomas. Prof. Alexander Muacevic, M.D., European CyberKnife Center, Munich, Germany.

CyberKnife Functional

Publications

Conti A, Acker G, Pontoriero A, Hardt J, Kluge A, Cacciola A, Iatì G, Kufeld M, Budach V, Vajkoczy P, Beltramo G, Pergolizzi S, Bergantin A, Loebel F, Parisi S, Senger C, Romanelli P. Factors affecting outcome in frameless non-isocentric stereotactic radiosurgery for trigeminal neuralgia: a multicentric cohort study. Radiat Oncol. 2020 May 22;15(1):115.
Romanelli P, Conti A, Redaelli I, Martinotti AS, Bergantin A, Bianchi LC, Beltramo G. Cyberknife Radiosurgery for Trigeminal Neuralgia. Cureus. 2019 Oct 28;11(10):e6014.
Romanelli P, Conti A, Bianchi L, Bergantin A, Martinotti A, Beltramo G. Image-Guided Robotic Radiosurgery for Trigeminal Neuralgia. Neurosurgery. 2018 Nov 1;83(5):1023-1030.

Videos

Image-Guided Robotic Radiosurgery for Trigeminal Neuralgia. Pantaleo Romanelli, M.D., CyberKnife Center, CDI, Milan, Italy.

CyberKnife Vascular Lesions

Publications

Kelly R, Conte A, Nair MN, Voyadzis JM, Anaizi A, Collins S, Kalhorn C, Stemer A, Mai J, Armonda R, Lischalk J, Berkowitz F, Nayar V, McGrail K, Collins BT. Arteriovenous Malformations Treated With Frameless Robotic Radiosurgery Using Non-Invasive Angiography: Long-Term Outcomes of a Single Center Pilot Study. Front Oncol. 2020 Nov 30;10:570782.
Rashad S, Endo T, Ogawa Y, Sato K, Endo H, Matsumoto Y, Takahashi A, Tominaga T. Stereotactic radiosurgery as a feasible treatment for intramedullary spinal arteriovenous malformations: a single-center observation. Neurosurg Rev. 2017 Apr;40(2):259-266.
Kalani MA, Choudhri O, Gibbs IC, Soltys SG, Adler JR, Thompson PA, Tayag AT, Samos CH, Chang SD. Stereotactic radiosurgery for intramedullary spinal arteriovenous malformations. J Clin Neurosci. 2016 Jul;29:162-7.
Oermann EK, Murthy N, Chen V, Baimeedi A, Sasaki-Adams D, McGrail K, Collins SP, Ewend MG, Collins BT. A multicenter retrospective study of frameless robotic radiosurgery for intracranial arteriovenous malformation. Front Oncol. 2014 Nov 4;4:298.
Potharaju M, John R, Venkataraman M, Gopalakrishna K, Subramanian B. Stereotactic radiosurgery results in three cases of intramedullary spinal cord arteriovenous malformations. Spine J. 2014 Nov 1;14(11):2582-8.
Ding C, Solberg TD, Hrycushko B, Medin P, Whitworth L, Timmerman RD. Multi-staged robotic stereotactic radiosurgery for large cerebral arteriovenous malformations. Radiother Oncol. 2013 Dec;109(3):452-6.
Colombo F, Cavedon C, Casentini L, Francescon P, Causin F, Pinna V. Early results of CyberKnife radiosurgery for arteriovenous malformations. J Neurosurg. 2009 Oct;111(4):807-19.

Videos

CyberKnife® Radiosurgery for AVMs: Using High-Definition Rotational Angiographic Imaging. Aditya Gupta M.D., Artemis Hospital, Gurgaon, Delhi NCR, India.

CyberKnife Spinal Metastases

Publications

Hirai R, Ohkubo YU, Igari M, Kumazaki YU, Aoshika T, Ryuno Y, Saito S, Abe T, Noda SE, Kato S. Time Dependence of Intra-fractional Motion in Spinal Stereotactic Body Radiotherapy. In Vivo. 2021 Jul-Aug;35(4):2433-2437.
Ehret F, Senger C, Kufeld M, Fürweger C, Kord M, Haidenberger A, Windisch P, Rueß D, Kaul D, Ruge M, Schichor C, Tonn JC, Muacevic A. Image-Guided Robotic Radiosurgery for the Management of Intramedullary Spinal Cord Metastases-A Multicenter Experience. Cancers (Basel). 2021 Jan 15;13(2)
Pontoriero A, Iatì G, Cacciola A, Conti A, Brogna A, Siragusa C, Ferini G, Davì V, Tamburella C, Molino L, Cambareri D, Severo C, Parisi S, Settineri N, Ielo I, Pergolizzi S. Stereotactic Body Radiation Therapy With Simultaneous Integrated Boost in Patients With Spinal Metastases. Technol Cancer Res Treat. 2020 Jan-Dec;19: 1533033820904447.
Mehta N, Zavitsanos PJ, Moldovan K, Oyelese A, Fridley JS, Gokaslan Z, Kinsella TJ, Hepel JT. Local failure and vertebral body fracture risk using multifraction stereotactic body radiation therapy for spine metastases. Adv Radiat Oncol. 2018 Apr 10;3(3):245-251.
Azad TD, Esparza R, Chaudhary N, Chang SD. Stereotactic radiosurgery for metastasis to the craniovertebral junction preserves spine stability and offers symptomatic relief. J Neurosurg Spine. 2016 Feb;24(2):241-247.
Gill B, Oermann E, Ju A, Suy S, Yu X, Rabin J, Kalhorn C, Nair MN, Voyadzis JM, Unger K, Collins SP, Harter KW, Collins BT. Fiducial-free CyberKnife stereotactic body radiation therapy (SBRT) for single vertebral body metastases: acceptable local control and normal tissue tolerance with 5 fraction approach. Front Oncol. 2012 Apr 26;2:39.

TomoTherapy Intracranial

Publications

Arpa D, Parisi E, Ghigi G, Savini A, Colangione SP, Tontini L, Pieri M, Foca F, Polico R, Tesei A, Sarnelli A, Romeo A. Re-irradiation of recurrent glioblastoma using helical TomoTherapy with simultaneous integrated boost: preliminary considerations of treatment efficacy. Sci Rep. 2020 Nov 9;10(1):19321
Koide Y, Tomita N, Adachi S, Tanaka H, Tachibana H, Kodaira T. Retrospective analysis ofhypofractionated stereotactic radiotherapy for tumors larger than 2 cm. Nagoya J Med Sci. 2019 Aug;81(3):397-406.
Saw CB, Gillette C, Peters CA, Koutcher L. Clinical implementation of radiosurgery using the Helical TomoTherapy unit. Med Dosim. 2018 Autumn;43(3):284-29
Murai T, Hayashi A, Manabe Y, Sugie C, Takaoka T, Yanagi T, Oguri T, Matsuo M, Mori Y, Shibamoto Y. Efficacy of stereotactic radiotherapy for brain metastases using dynamic jaws technology in the helical tomotherapy system. Br J Radiol. 2016 Oct;89(1066):20160374.
Bruni A, Gaito S, Ciarmatori A, Lanfranchi B, Mazzeo E, Maffei N, Giacobazzi P, Turco E, Guidi G, Bertoni F. Radiosurgery Using Tomotherapy for Patients with Brain Oligo-metastasis: A Retrospective Analysis on Feasibility and Tolerance. Anticancer Res. 2015 Dec;35(12):6805-12.
Barra S, Agostinelli S, Vagge S, Giannelli F, Siccardi D, Garelli S, Aloi D, Belgioia L, Bosetti D, Zeverino M, Corvò R. Radiosurgery with Helical Tomotherapy: Outcomes for Patients with One or Multifocal Brain Metastasis. Technol Cancer Res Treat. 2015 Dec;14(6):693-9