30 Years of Evidence

Take a moment to explore a selection of publications and conference abstracts from around the globe. Find evidence for a wide range of treatment sites including malignant and benign disease, different fractionation schedules and real-time motion synchronization techniques for the CyberKnife® and Radixact®/ TomoTherapy® platforms. We update new papers on a regular basis. See how health professionals are helping to improve patient outcomes.

Time-resolved Biological Effective Dose Distributions in Stereotactic Radiosurgery for Vestibular Schwannomas: A Comparative Analysis Between Two Dedicated Stereotactic Radiosurgery Systems

Moutsatsos A, Cotrutz C, Stergioula A, Tuleasca C, Pantelis E | Phys Med Biol | 2025

Long-term Outcomes of Ablative Stereotactic Body Radiation Therapy for Inoperable, Non-metastatic Pancreatic Cancer

Cao BY, Zhang LT, Wu CC, Wang J | Radiother Oncol. | 2025

Investigating the Efficacy and Safety of the CyberKnife System for Treating Primary Pancreatic Cancer with Metastases to the Gastrointestinal Tract

Zhang Z, Tian B, Xu H, Huang H, Liang X, Bo C, Bian Y, Wei M, Zhao Z | Cancer Manag Res | 2025

Impact of CyberKnife Radiosurgery on Median Overall Survival of Various Parameters in Patients with 1-12 Brain Metastases

Stereotactic Reirradiation with CyberKnife for Locally Recurrent Prostate Cancer, Long-term Toxicity and Clinical Outcomes from a Monocentric Cohort

Francolini G, Carnevale MG, Di Cataldo V, Loi M, Detti B, Orsatti C, Caprara L, Bertini N, Lorenzetti V, Olmetto E, Becherini C, Visani L, Salvestrini V, Simontacchi G, Greto D, Bonomo P, Doro R, Masi L, Desideri I, Meattini I, Serni S, Livi L | Radiol Med | 2023

Intensity Modulated Radiation Therapy with Stereotactic Body Radiation Therapy Boost for Unfavorable Prostate Cancer: Five-year Outcomes

Carrasquilla M, Sholklapper T, Pepin AN, Hodgins N, Lei S, Rashid A, Danner M, Zwart A, Bolanos G, Ayoob M, Yung T, Aghdam N, Collins B, Suy S, Kumar D, Hankins R, Kowalczyk K, Dawson N, Collins S | Front Oncol | 2023

Accuracy of Robotic Radiosurgery in Renal Cell Carcinoma

Hofmann T, Kohlhase N, Eftimova D, Eder MM, Staehler M, Ruge MI, Muacevic A, Fürweger C | Phys Med | 2024

Revisiting Radioresistance: A Systematic Review of Outcomes of Stereotactic Radiosurgery (SRS) in Functional Head and Neck Paragangliomas

Verma O, Mantziaris G, Das L, Sheehan JP, Tripathi M | Neurosurg Rev. | 2025

Hypofractionated Radiosurgery (25 Gy/5 fractions) for Optic Nerve Sheath Meningiomas: Results from an Exploratory Phase 2 Prospective Trial

Fariselli L, Marzoli SB, Morlino S, Pinzi V, Pedone C, De Martin E, Romeo A, Tramacere I, Marchetti M | Int J Radiat Oncol Biol Phys. | 2025

Efficacy and Safety of Donut-Shaped Circumferential Spine CyberKnife Stereotactic Body Radiotherapy for Metastatic Spine Disease

Park DJ, Lee I, Annagiri S, Chou KN, Zamarud A, Akhavan-Sigari A, Hori YS, Persad AR, Abu-Reesh D, Lam FC, Tayag A, Ustrzynski L, Emrich SC, Gu X, Pollom EL, Chang SD | Neurosurgery. | 2025

Computed Tomography Guided Online Adaptive Stereotactic Body Radiation Therapy for Lymph Node Oligometastases: Impact on Dose to Target and Organs at Risk

van Werkhoven LA, Milder MTW, Schillemans W, Hoogeman MS, Nout RA, Nuyttens JJ | Int J Radiat Oncol Biol Phys. | 2025

Pattern of Recurrence After Fractionated Stereotactic Reirradiation in Adult Glioblastoma

Margulies A, Sahki N, Rech F, Vogin G, Blonski M, Peiffert D, Taillandier L, Lesanne G, Demogeot N | Radiat Oncol. | 2025

Low-Burden Oligometastatic Disease of the Lung Treated with Robotic Stereotactic Ablative Radiotherapy: A Retrospective Study

Zygogianni A, Koukourakis IM, Liakouli Z, Desse D, Georgakopoulos I, Armpilia C, Lymperopoulou G, Kouloulias V | Biomedicines. | 2025

Risk-adapted Stereotactic Body Radiation Therapy for the Treatment of Large (>3 cm) Primary Lung Cancer with or without Histologic Confirmation: A Propensity Score Matched and Weighted Analysis

Zeng HY, Li YJ, Ji CZ, Wang HH, Yu XR, He Y, Bai H, Zheng BY, Yan YY, Xu JW, Zaorsky NG, Shi JM, Dong Y, Yu XY, Wang JS, Song YC, Yuan ZY, Chen Y, Meng MB. | Radiother Oncol. | 2025