BREAST CANCER AWARENESS 2021
Every Woman Deserves the Best Option for Breast Cancer Treatment
October is Breast Cancer Awareness Month, a time of year when people around the world, including the Accuray team, join together to honor the millions of breast cancer patients and survivors. Our legacy of patient-first innovation drives unique capabilities for the confident treatment of breast cancer.
A promising option for partial breast irradiation after breast-conserving surgery.
The true robotic precision and motion synchronization & real-time adaptive capabilities of the CyberKnife® System provides choices for early stage breast cancer patients treated post-lumpectomy.
Two recent clinical studies indicate stereotactic accelerated partial breast irradiation (APBI) delivered with the CyberKnife System and Synchrony technology enabled precise treatments while limiting toxicity and preserving cosmesis.
An effective clinical solution for routine and complex breast cancer treatments.
The Radixact® System, the next-generation TomoTherapy® platform, provides a personalized, precise and non-invasive option for treating breast cancer, typically a post-lumpectomy or mastectomy.
The system is the world’s first helical radiotherapy platform, delivering highly accurate radiation dose from 360 degrees around the patient. Multiple clinical studies show that the TomoTherapy System can provide excellent outcomes for breast cancer patients.
Clinical Studies Offer Hope for Breast Cancer Patients
ESTRO Abstracts
Breast
- PD-0779: Fiducial motion relative to tumor bed in partial breast irradiation and risk of geographical miss. N. Hoekstra1, S. Habraken1, A. Swaak – Kragten1, J. Pignol2, M. Hoogeman1. 1Erasmus MC Cancer Institute, Radiotherapy, Rotterdam, The Netherlands; 2Dalhousie University,
Radiotherapy, Halifax, Canada - PO-1138: Preoperative radiation therapy in breast cancer: preliminary results from ROCK trial (NCT03520894). V. Di Cataldo1, G. Francolini2, L. Visani1, C. Becherini2, E. Scoccimarro3, L. Masi1, R. Doro1, G. Salvatore4, S.Bianchi5, V. Vezzosi6, E. Lemmi6, J. Nori7, L. Sanchez8, L. Orzalesi8, M. Bernini8, M. Loi2, I. Desideri4, M.Mangoni4, I. Meattini4, L. Livi4. 1IFCA, Cyberknife, Florence, Italy; 2Azienda Ospedaliero-Universitaria Careggi, Radiation Oncology Unit, Oncology Department, Florence, Italy; 3University of Florence, Department of Experimental and Clinical Biomedical Sciences Mario Serio, Florence, Italy; 4University of Florence, Department of Biomedical, Experimental and Clinical Sciences “Mario Serio”, Florence, Italy; 5 Azienda Ospedaliero-Universitaria Careggi, Division of Pathological Anatomy, Florence, Italy; 6Azienda Ospedaliero-Universitaria Careggi, Division of Pathological Anatomy, Florence, Italy; 7Azienda Ospedaliero-Universitaria Careggi, Diagnostic Senology Unit, Florence, Italy; 8Azienda Ospedaliero-Universitaria Careggi, Breast Surgery Unit, Florence, Italy
TomoTherapy Treatment
Publications
- de Paula U, D’Angelillo RM, Andrulli AD, Apicella G, Caruso C, Ghini C, Gomellini S, Ponti E, Pompei M, Caccavari A, Petrocchi A, Costarelli L, Giordano M, La Pinta M, Meli EZ, Mauri M, Minelli M, Rossi R, Scavina P, Broglia L, Ponzani T, Loreti A, Fortunato L. Long-Term Outcomes of Once-Daily Accelerated Partial-Breast Irradiation With Tomotherapy: Results of a Phase 2 Trial. Int J Radiat Oncol Biol Phys. 2021 Mar 1;109(3):678-687.
- Bataille B, Raoudha B, Le Tinier F, Basson L, Escande A, Langin H, Tresch E, Crop F, Darloy F, Carlier D, Lartigau E, Pasquier D. Prospective Study of Intensity-Modulated Radiation Therapy for Locally Advanced Breast Cancer. Cancers (Basel). 2020 Dec 20;12(12)
- Joseph K, Vos LJ, Gabos Z, Pervez N, Chafe S, Tankel K, Warkentin H, Ghosh S, Amanie J, Powell K, Polkosnik LA, Horsman S, MacKenzie M, Sabri S, Parliament MB, Mackey J, Abdulkarim B. Skin Toxicity in Early Breast Cancer Patients Treated with Field-In-Field Breast Intensity-Modulated Radiotherapy versus Helical Inverse Breast Intensity-Modulated Radiotherapy: Results of a Phase III Randomised Controlled Trial. Clin Oncol (R Coll Radiol). 2020 Jul 22:S0936-6555(20)30287-9.
- Mathieu D, Bedwani S, Mascolo-Fortin J, Côté N, Bernard AA, Roberge D, Yassa M, Bahig H, Vu T. Cardiac Sparing with Personalized Treatment Planning for Early-stage Left Breast Cancer. Cureus. 2020 Mar 12;12(3):e7247.
- Chitapanarux I, Nobnop W, Tippanya D, Sripan P, Chakrabandhu S, Klunklin P, Onchan W, Jia-Mahasap B, Tharavichitkul E. Clinical outcomes and dosimetric study of hypofractionated Helical TomoTherapy in breast cancer patients. PLoS One. 2019 Jan 31;14(1):e0211578.
- Arsene-Henry A, Foy JP, Robilliard M, Xu HP, Bazire L, Peurien D, Poortmans P, Fourquet A, Kirova YM. The use of helical tomotherapy in the treatment of early stage breast cancer: indications, tolerance, efficacy-a single center experience. Oncotarget. 2018 May 4;9(34):23608-23619.
- Thery L, Arsene-Henry A, Carroll S, Peurien D, Bazire L, Robilliard M, Fourquet A, Kirova YM. Use of helical tomotherapy in locally advanced and/or metastatic breast cancer for locoregional treatment. Br J Radiol. 2018 May;91(1085):20170822.
- Orecchia R, Rojas DP, Cattani F, Ricotti R, Santoro L, Morra A, Cambria R, Luraschi R, Dicuonzo S, Ronchi S, Surgo A, Dell’ Acqua V, Veronesi P, De Lorenzi F, Fodor C, Leonardi MC, Jereczek-Fossa BA. Hypofractionated postmastectomy radiotherapy with helical tomotherapy in patients with immediate breast reconstruction: dosimetric results and acute/intermediate toxicity evaluation. Med Oncol. 2018 Feb 13;35(3):39.
Videos
- Clinical Outcomes and Dosimetric Study of Hypofractionated Helical TomoTherapy® in Breast Cancer Patients. Imjai Chitapanarux M.D., Chiang Mai University, Chiang Mai, Thailand.
- A Comprehensive Radiotherapy Strategy for Managing Breast Cancer. Rupesh Kotecha, M.D., Miami Cancer Institute, Miami, FL, USA.
- Breast Cancer: Your Challenges Today – Our Solutions for Tomorrow. Nathan Corradini, MS, DABR, SSRMP, Clinica Luganese, Lugano, Switzerland, Carole Massabeau, M.D., Institut Universitaire du Cancer de Toulouse Oncopole, Toulouse, France, and Jennifer R. Bellon, M.D. Dana-Farber Cancer Institute, Boston, MA, USA.
CyberKnife Treatment
Publications
- Rahimi A, Morgan HE, Kim DW, Zhang Y, Leitch M, Wooldridge R, Goudreau S, Haley B, Rao R, Rivers A, Spangler AE, Jones RT, Stevenson S, Staley J, Albuquerque K, Ahn C, Neufeld S, Alluri PG, Ding C, Garwood D, Seiler S, Zhao B, Gu X, Timmerman R. Cosmetic Outcomes of a Phase 1 Dose Escalation Study of 5-Fraction Stereotactic Partial Breast Irradiation for Early Stage Breast Cancer. Int J Radiat Oncol Biol Phys. 2021 Jul 1;110(3):772-782.
- Rahimi A, Zhang Y, Kim DW, Morgan H, Hossain F, Leitch M, Wooldridge R, Seiler S, Goudreau S, Haley B, Rao R, Rivers A, Spangler A, Ahn C, Stevenson S, Staley J, Albuquerque K, Ding C, Gu X, Zhao B, Timmerman R. Risk Factors for Fat Necrosis After Stereotactic Partial Breast Irradiation for Early-Stage Breast Cancer in a Phase 1 Clinical Trial. Int J Radiat Oncol Biol Phys. 2020 Nov 1;108(3):697-706.
- Mészáros N, Smanykó V, Major T, Stelczer G, Jánváry L, Kovács E, Mária B, Zaka Z, Pukancsik D, Takácsi-Nagy Z, Polgár C. Implementation of Stereotactic Accelerated Partial Breast Irradiation Using CyberKnife – Technical Considerations and Early Experiences of a Phase II Clinical Study. Pathol Oncol Res. 2020 Oct;26(4):2307-2313.
- Lee WH, Chang JS, Kim MJ, Park VY, Yoon JH, Kim SY, Kim JY, Park HS, Kim SI, Cho YU, Park BW, Kim YB. First Experience in Korea of Stereotactic Partial Breast Irradiation for Low-Risk Early-Stage Breast Cancer. Front Oncol. 2020 Apr 29;10:672.
- Rahimi A, Thomas K, Spangler A, Rao R, Leitch M, Wooldridge R, Rivers A, Seiler S, Albuquerque K, Stevenson S, Goudreau S, Garwood D, Haley B, Euhus D, Heinzerling J, Ding C, Gao A, Ahn C, Timmerman R. Preliminary Results of a Phase 1 Dose-Escalation Trial for Early-Stage Breast Cancer Using 5-Fraction Stereotactic Body Radiation Therapy for Partial-Breast Irradiation. Int J Radiat Oncol Biol Phys. 2017 May 1;98(1):196-205.e2.
- Seiler S, Rahimi A, Choudhery S, Garwood D, Spangler A, Cherian S, Goudreau S. Ultrasound-Guided Placement of Gold Fiducial Markers for Stereotactic Partial-Breast Irradiation. AJR Am J Roentgenol. 2016 Sep;207(3):685-8.
Videos
- CyberKnife® System Experience for Partial Breast Irradiation. Asal Rahimi M.D. M.S., UT Southwestern Medical Center, Dallas, TX, USA.
